WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 | Human,Mouse,Rat |
ICC | 1/50-1/200 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | ERIC-1; ERIC1; TAC3; Transforming acidic coiled-coil-containing protein 3;TACC3;;TACC3 |
WB Predicted band size | Calculated MW: 90 kDa ; Observed MW: 140 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human TACC3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于TACC3抗体的3-4篇示例参考文献(注:以下为假设性示例,实际引用请核实真实文献):
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1. **"TACC3 expression in breast cancer: Clinical significance and antibody-based detection"**
*Lauffart, B. et al. (2015).*
摘要:研究利用特异性TACC3抗体,通过免疫组化分析乳腺癌组织中TACC3蛋白的表达水平,发现其过表达与肿瘤分级和不良预后显著相关,提示其作为潜在生物标志物的价值。
2. **"Functional characterization of anti-TACC3 antibodies in cancer cell proliferation"**
*Huang, Y. et al. (2018).*
摘要:开发了一种高特异性TACC3单克隆抗体,体外实验显示其可抑制肿瘤细胞的有丝分裂和增殖,机制与干扰纺锤体稳定性及阻滞细胞周期相关。
3. **"Structural insights into TACC3-antibody interactions by cryo-EM"**
*Gómez-Balderas, R. et al. (2020).*
摘要:通过冷冻电镜解析TACC3蛋白与其单克隆抗体的复合物结构,揭示了抗体结合域的关键位点,为靶向TACC3的抗体药物设计提供结构基础。
4. **"TACC3 antibody application in myeloma research"**
*Barton, E. et al. (2019).*
摘要:研究在多发性骨髓瘤模型中利用TACC3抗体进行功能阻断实验,证明TACC3通过调控Aurora激酶信号通路促进肿瘤存活,抗体干预可显著增强化疗敏感性。
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**提示**:实际研究中,建议通过PubMed或Google Scholar以关键词“TACC3 antibody”或“anti-TACC3”检索最新文献,并优先选择高影响力期刊或权威团队的研究成果。
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