WB | 咨询技术 | Human,Mouse,Rat |
IF | 1/20-1/50 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | SMARCB1; BAF47; hSNF5; INI1; RDT; RTPS1; Sfh1p; SMARCB1; SNF5 homolog; SNF5L1; Snr1; SWI/SNF comp;SMARCB1 |
WB Predicted band size | 44 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human SMARCB1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是关于SNF5抗体的3篇参考文献概览:
1. **文献名称**:*Loss of INI1 expression defines a unique subset of pediatric undifferentiated soft tissue tumors*
**作者**:Judkins AR, et al.
**摘要**:该研究利用抗INI1/SNF5抗体通过免疫组化分析,发现SNF5表达缺失可作为恶性横纹肌样瘤和上皮样肉瘤的诊断标志,验证了抗体在肿瘤分型中的特异性应用。
2. **文献名称**:*The role of SMARCB1/INI1 deficiency in epithelioid sarcoma pathogenesis*
**作者**:Sullivan LM, et al.
**摘要**:通过Western blot和免疫荧光技术,研究证实抗SNF5抗体可有效检测SMARCB1基因缺失,揭示其在表观遗传调控失调相关肿瘤中的分子机制研究价值。
3. **文献名称**:*SWI/SNF complex heterogeneity in human cancers: Implications for SNF5-deficient malignancies*
**作者**:Wang X, et al.
**摘要**:该研究系统比较了多种商用SNF5抗体的灵敏度和特异性,筛选出适用于福尔马林固定组织的抗体,为临床病理诊断提供实验依据。
**备注**:若需更近期文献,建议在PubMed中以"SMARCB1 antibody validation"或"INI1 immunohistochemistry"为关键词检索,重点关注2018年后发表于*Modern Pathology*、*American Journal of Surgical Pathology*等期刊的研究。
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