WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | C10orf63; ENKUR; Enkurin;;Enkurin |
WB Predicted band size | 29 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | A synthesized peptide derived from human Enkurin |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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关于C10orf63抗体的研究目前较为有限,公开数据库及主流期刊中可查的针对性研究较少。以下是基于假设性数据的示例(请注意,这些文献并非真实存在,仅用于演示格式):
1. **"Characterization of C10orf63 Protein Expression in Human Tissues Using a Novel Polyclonal Antibody"**
*Authors: Smith A, et al.*
*摘要*:本研究开发了一种针对C10orf63的多克隆抗体,通过免疫组化和Western blot技术,首次报道了C10orf63在多种人体组织中的差异性表达,提示其潜在生理功能。
2. **"C10orf63 Antibody Validation for Immunoprecipitation in Cancer Cell Lines"**
*Authors: Lee B, et al.*
*摘要*:文章验证了一种商业化C10orf63抗体的特异性,证明其可用于免疫共沉淀(IP)实验,并发现C10orf63与特定信号通路蛋白在癌细胞中的相互作用。
3. **"Role of C10orf63 in Neuronal Development: Insights from Antibody-Based Knockdown Assays"**
*Authors: García R, et al.*
*摘要*:利用C10orf63抗体进行功能缺失实验,发现该基因在神经元分化中可能调控突触形成,为神经发育障碍研究提供新方向。
4. **"Comparative Analysis of C10orf63 Antibody Specificity Across Species"**
*Authors: Tanaka K, et al.*
*摘要*:评估了多种C10orf63抗体的交叉反应性,发现部分抗体在小鼠和大鼠模型中存在非特异性结合,强调了抗体选择对跨物种研究的重要性。
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**提示**:若需真实文献,建议通过以下途径获取:
1. 查询抗体公司(如Abcam、Sigma-Aldrich)产品页引用的文献;
2. 在PubMed或Google Scholar以“C10orf63 AND (antibody OR immunohistochemistry)”为关键词检索;
3. 关注基因功能研究中的方法学描述(可能提及抗体使用)。
The C10orf63 antibody is a research tool designed to target the protein encoded by the C10orf63 gene, located on human chromosome 10. This gene, also known as "chromosome 10 open reading frame 63." remains poorly characterized, with limited information on its precise biological functions or involvement in specific pathways. Current genomic databases suggest it encodes a protein of unknown structure and activity, though computational analyses predict potential roles in cellular processes like intracellular signaling or protein interactions.
C10orf63 antibodies are primarily utilized in basic research to investigate the protein’s expression patterns, subcellular localization, and tissue distribution. They enable techniques such as Western blotting, immunohistochemistry, and immunofluorescence, aiding in the exploration of its potential associations with diseases. While no direct disease links are firmly established, chromosome 10 abnormalities have been implicated in cancers, neurological disorders, and developmental conditions, sparking interest in C10orf63 as a candidate for further study.
These antibodies are typically produced in host species like rabbits or mice, often validated for specificity using knockout controls or recombinant protein. However, the lack of extensive functional data on C10orf63 necessitates cautious interpretation of experimental results. Ongoing research aims to clarify its physiological relevance, with antibodies serving as critical tools to unravel its role in health and disease.
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