Mouse Monoclonal KIAA1967 Antibody

The KIAA1967 antibody is a research tool designed to target the KIAA1967 protein, a less characterized gene product encoded by the KIAA1967 gene (also known as CCDC36 or C12orf29). This gene is conserved across species and has been implicated in various cellular processes, including DNA repair, chromatin remodeling, and cell cycle regulation. The protein is believed to play a role in maintaining genomic stability, though its exact molecular mechanisms remain under investigation. KIAA1967 antibodies are typically developed as polyclonal or monoclonal antibodies, often raised in rabbits or mice using immunogenic peptides or recombinant protein fragments. They are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study the protein's expression, localization, and interaction partners in cell lines or tissue samples. Some studies suggest KIAA1967 may be dysregulated in cancers, such as breast or ovarian tumors, linking it to oncogenic pathways. Validation of these antibodies often includes knockout cell line controls or siRNA knockdown to confirm specificity. Commercial suppliers provide KIAA1967 antibodies with varying validation data, requiring careful optimization for experimental conditions. Ongoing research aims to clarify its biological roles and potential therapeutic relevance in human diseases.