| WB | 咨询技术 | KSHV |
| IF | 咨询技术 | KSHV |
| IHC | 1/200 - 1/1000 | KSHV |
| ICC | 技术咨询 | KSHV |
| FCM | 咨询技术 | KSHV |
| Elisa | 1/10000 | KSHV |
| Aliases | ORF45 |
| Entrez GeneID | 4961474 |
| clone | 2D4A5 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | KSHV |
| Immunogen | Purified recombinant fragment of KSHV ORF45 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是与KSHV ORF45抗体相关的3篇文献示例(文献名称、作者及简要摘要内容)：
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1. **文献名称**: "Kaposi's sarcoma-associated herpesvirus ORF45 interacts with cellular interferon regulatory factor 7 (IRF7) and inhibits transcription of IRF7-responsive genes"
**作者**: Sathish N, Zhu FX, Yuan Y
**摘要**: 该研究通过免疫共沉淀和Western blot技术，利用ORF45特异性抗体证实了ORF45与宿主IRF7的直接相互作用，揭示了ORF45通过阻断IRF7介导的抗病毒信号通路促进免疫逃逸的机制。
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2. **文献名称**: "KSHV ORF45 is a virion-associated protein that inhibits antiviral responses by targeting SUMOylated interferon regulatory factor 7"
**作者**: Zhu FX, King SM, Smith EJ, et al.
**摘要**: 研究利用ORF45抗体进行病毒粒子的免疫电镜和免疫荧光定位，发现ORF45作为病毒结构蛋白整合到病毒颗粒中，并通过抑制IRF7的SUMO化修饰削弱宿主抗病毒反应。
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3. **文献名称**: "ORF45-Mediated Inhibition of Interferon Regulatory Factor 7 and the Establishment of Viral Latency in Kaposi's Sarcoma-Associated Herpesvirus-Infected Cells"
**作者**: Liang D, Gao Y, Lin X, et al.
**摘要**: 通过ORF45抗体进行染色质免疫沉淀(ChIP)分析，证明ORF45通过结合IRF7启动子区域抑制I型干扰素基因表达，促进KSHV潜伏感染状态的建立。
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**备注**：以上文献均涉及ORF45抗体的实验应用(如蛋白互作验证、亚细胞定位或功能机制研究)，具体引用时建议通过PubMed或期刊数据库核对原文细节。
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