| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | ZNF566 |
| Uniprot No | Q969W8 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-418 aa |
| 活性数据 | MAQESVMFSDVSVDFSQEEWECLNDDQRDLYRDVMLENYSNLVSMGHSISKPNVISYLEQGKEPWLADRELTRGQWPVLESRCETKKLFLKKEIYEIESTQWEIMEKLTRRDFQCSSFRDDWECNRQFKKELGSQGGHFNQLVFTHEDLPTLSHHPSFTLQQIINSKKKFCASKEYRKTFRHGSQFATHEIIHTIEKPYECKECGKSFRHPSRLTHHQKIHTGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYECKECGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFSQSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQRIHTGEKPYECKICGKAYSQSSQLISHHRIHTSEKPYEYRECGKNFNYDPQLIQHQNLYW |
| 分子量 | 75.6 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下为假设性示例(具体文献需根据实际检索结果调整，ZNF566相关研究可能较少)：
1. **《ZNF566基因的克隆表达及生物信息学分析》**
- 作者：李明等
- 摘要：研究通过PCR技术克隆人ZNF566基因，构建原核表达载体并纯化重组蛋白，预测其锌指结构域参与DNA结合功能。
2. **《ZNF566通过调控Wnt信号通路抑制肿瘤细胞增殖》**
- 作者：Smith J, et al.
- 摘要：利用重组ZNF566蛋白处理癌细胞，发现其能下调Wnt通路靶基因表达，提示其可能的抑癌机制。
3. **《重组ZNF566蛋白在神经发育中的表观遗传调控作用》**
- 作者：Chen X, et al.
- 摘要：体外实验表明，ZNF566可与特定DNA甲基化转移酶互作，影响神经元分化相关基因的甲基化水平。
**提示**：ZNF566研究可能较少，建议通过PubMed或Google Scholar结合关键词(如“ZNF566 recombinant protein”、“zinc finger protein 566 function”)获取最新文献。
**Background of Recombinant Human ZNF566 Protein**
Zinc finger protein 566 (ZNF566) is a member of the zinc finger protein family, characterized by conserved Cys₂His₂ (C2H2)-type zinc finger domains that facilitate DNA or RNA binding. These proteins are implicated in transcriptional regulation, chromatin remodeling, and cellular processes like differentiation and apoptosis. ZNF566. encoded by the *ZNF566* gene, is believed to function as a transcription factor, though its precise biological roles remain under investigation.
Recombinant human ZNF566 protein is engineered via genetic engineering techniques, often expressed in bacterial or mammalian systems to ensure proper folding and post-translational modifications. Its recombinant form enables functional studies, such as elucidating interactions with nucleic acids or proteins, and exploring its involvement in signaling pathways or disease mechanisms.
Emerging research suggests ZNF566 may contribute to cancer progression, neurological disorders, or immune regulation, though mechanistic details are sparse. Its recombinant version serves as a critical tool for *in vitro* assays, antibody production, and high-throughput screening to identify potential therapeutic targets. Further studies are required to fully unravel its physiological and pathological significance, highlighting its potential in both basic research and biomedical applications.
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