| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | ZNF562 |
| Uniprot No | Q6V9R5 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-426 aa |
| 活性数据 | MSAFDMSHGFFPREPICPFEEKTKIGTMVEDHRSNSYQDSVTFDDVAVEFTPEEWALLDTTQKYLYRDVMLENYMNLASVDFFFCLTSEWEIQPRTKRSSLQQGFLKNQIFTGIQMQTRSYSGWKLCENCGEVFSEQFCLKTHMRAQNGGNTFEGNCYGKDSISVHKEASIGQELSKFNPCGKVFTLTPGLAVHLEILNGRQPYKCKECGKGFKYFASLDNHMGIHIGEKLCEFQECERAITTSSHLKQCVAVHTGKKSEKTKNCGKSFTNFSQLSAHAKTHKGEKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCTECGKAFTRSTHLTQHVRTHTGIKPYECKECGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFITSSHRSKHLKTHSGER |
| 分子量 | 46.9 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人ZNF562蛋白的3篇示例参考文献(注：部分内容为虚构，仅供示例参考)：
1. **文献名称**：*ZNF562 promotes hepatocellular carcinoma progression by regulating cell cycle-related genes*
**作者**：Zhang, W., et al.
**摘要**：该研究通过生物信息学分析与实验验证，发现ZNF562在肝癌组织中显著高表达，并通过激活CDK2和Cyclin E1等基因加速细胞周期进程，促进肿瘤细胞增殖。
2. **文献名称**：*Epigenetic regulation by ZNF562 in maintaining pluripotency of human embryonic stem cells*
**作者**：Johnson, A. L., et al.
**摘要**：研究表明，ZNF562通过招募组蛋白乙酰转移酶复合物至多能性基因(如OCT4、NANOG)的启动子区域，增强染色质开放性，从而维持胚胎干细胞的自我更新能力。
3. **文献名称**：*ZNF562 interacts with DNA damage response proteins and modulates genomic stability*
**作者**：Chen, H., et al.
**摘要**：蛋白质互作实验发现ZNF562与ATM激酶和BRCA1存在物理结合，其缺失会导致DNA双链断裂修复延迟，提示其在基因组稳定性中发挥关键作用。
(提示：实际研究中建议通过PubMed或Web of Science检索最新文献，确保引用准确性。)
Zinc finger protein 562 (ZNF562) is a member of the zinc finger protein family, characterized by conserved Cys₂His₂ (C₂H₂)-type zinc finger domains that mediate sequence-specific DNA or RNA binding. As a transcription regulator, ZNF562 is hypothesized to participate in modulating gene expression, though its precise biological roles remain unclear. Structurally, it contains multiple tandem zinc finger motifs, potentially enabling interactions with nucleic acids or proteins. Genomic studies suggest ZNF562 may influence cellular processes such as differentiation, proliferation, or apoptosis, possibly through epigenetic regulation or signaling pathway modulation. Its expression has been detected in various tissues, with altered levels observed in certain cancers, implying potential links to tumorigenesis or disease progression.
Recombinant human ZNF562 protein, produced via heterologous expression systems (e.g., *E. coli* or mammalian cells), enables functional studies to elucidate its molecular mechanisms. This engineered protein allows *in vitro* analyses, including DNA/RNA binding assays, protein interaction mapping, and enzymatic activity tests. Researchers employ it to investigate ZNF562’s role in chromatin remodeling, post-translational modifications, or its crosstalk with other regulatory factors. Decoding ZNF562’s functions could advance understanding of its contributions to developmental disorders, oncogenesis, or immune responses, offering insights for therapeutic targeting. However, comprehensive characterization of its targets and pathways remains a critical knowledge gap.
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