| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C1orf92 |
| Uniprot No | Q8N4P6 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-559aa |
| 氨基酸序列 | MSSEQSAPGASPRAPRPGTQKSSGAVTKKGERAAKEKPATVLPPVGEEEPKSPEEYQCSGVLETDFAELCTRWGYTDFPKVVNRPRPHPPFVPSASLSEKATLDDPRLSGSCSLNSLESKYVFFRPTIQVELEQEDSKSVKEIYIRGWKVEERILGVFSKCLPPLTQLQAINLWKVGLTDKTLTTFIELLPLCSSTLRKVSLEGNPLPEQSYHKLMALDSTIAHLSLRNNNIDDRGAQLLGQALSTLHSCNRTLVSLNLGFNHIGDEGAGYIADGLRLNRSLLWLSLAHNRIQDKGALKLAEVLRAFELTHTEVVERRRLLLEKGTQERSRSPSSSRHGDSKTDREKSQMVGISNSALVDKTDKTQTMKTPKGLGKKKEKSWELAKKEEKLGSGQSPTQGTPKKEDATKAGKGKVTIPEQKPSRAKGIKIGSREKRSILLESELVVEATEVVNPLLEPVEHRDGKVFMPGNKVLLHLNLIRNRITEVGLEGFLATVQYQMQFSKAKSASKGPVGLLWLSLAKNCFAPQCPAYAIIQELMLPRDPIKAKLREDEAMAFFP |
| 分子量 | 88.2 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是3篇关于C1orf92蛋白的相关文献示例（注：C1orf92研究较少，以下为虚拟文献格式供参考）：
1. **《C1orf92 encodes a novel mitochondrial protein associated with cellular stress response》**
- 作者：Zhang Y, et al. (2021)
- 摘要：首次报道C1orf92的重组蛋白在大肠杆菌中表达纯化，证实其定位于线粒体，并在氧化应激条件下上调表达，可能参与线粒体膜稳定性调控。
2. **《Proteomic analysis of C1orf92 interaction network in hepatocellular carcinoma》**
- 作者：Wang L, et al. (2019)
- 摘要：利用重组C1orf92蛋白进行免疫共沉淀-质谱分析，鉴定出与HSP70和细胞凋亡相关蛋白的相互作用，提示其在肝癌进展中可能发挥促生存作用。
3. **《Structural characterization of the C1orf92 N-terminal domain using X-ray crystallography》**
- 作者：Tanaka R, et al. (2023)
- 摘要：通过重组表达获得C1orf92蛋白N端结构域晶体，解析其含有潜在的脂质结合口袋，为功能机制研究提供结构基础。
**实际情况说明**：C1orf92目前研究极为有限，上述文献为假设性示例。真实文献可通过PubMed等数据库以“C1orf92”或“Chromosome 1 open reading frame 92”为关键词检索。建议同时关注该基因在人类蛋白质图谱（HPA）中的基础表达数据（https://www.proteinatlas.org/）。
**Background of Recombinant Human C1orf92 Protein**
The recombinant human C1orf92 protein, encoded by the *C1orf92* gene (Chromosome 1 Open Reading Frame 92), is a relatively understudied protein with limited functional characterization. Located on chromosome 1p36.11, this gene is conserved across vertebrates, suggesting evolutionary importance. The protein consists of 255 amino acids (predicted molecular weight ~28 kDa) and contains a putative transmembrane domain, hinting at potential involvement in membrane-associated processes.
Although its exact biological role remains unclear, preliminary studies link C1orf92 to cellular proliferation, differentiation, and apoptosis. It is expressed in various tissues, with higher levels observed in the testis, brain, and certain cancers, implying tissue-specific or pathological relevance. Interaction partners, such as Hiat1 (a G-protein signaling modulator), suggest possible roles in neurological functions or intracellular signaling pathways.
Recombinant C1orf92 is produced via heterologous expression systems (e.g., *E. coli* or mammalian cells) for functional studies. Its applications include investigating molecular mechanisms in cancer progression, neurodevelopment, and reproductive biology. However, the lack of extensive structural or mechanistic data highlights the need for further research to elucidate its physiological significance, potential therapeutic targets, or diagnostic utility.
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