| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 1/200-1/1000 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/20000 | Human,Mouse,Rat |
| Aliases | OR6Q1; Olfactory receptor 6Q1; Olfactory receptor OR11-226 |
| Entrez GeneID | 219952; |
| WB Predicted band size | 36kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from the Internal region of human Olfactory receptor 6Q1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
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以下是关于Olfactory receptor 6Q1(OR6Q1)抗体的模拟参考文献示例(实际文献需通过PubMed或专业数据库验证)：
1. **文献名称**: "Expression and functional characterization of Olfactory Receptor 6Q1 in non-olfactory tissues"
**作者**: Zhang, X. et al.
**摘要**: 本研究利用特异性OR6Q1抗体检测了其在前列腺和睾丸组织中的表达，发现其可能参与细胞信号调控，并与前列腺癌进展相关。
2. **文献名称**: "Development of a monoclonal antibody for OR6Q1 and its application in olfactory receptor screening"
**作者**: Smith, J.R. & Lee, K.
**摘要**: 报道了一种高特异性OR6Q1单克隆抗体的开发，通过免疫组化和Western blot验证其在嗅觉神经元及肺癌细胞系中的定位。
3. **文献名称**: "Olfactory receptor 6Q1 mediates cancer cell migration via ligand-dependent pathways"
**作者**: Lee, S. et al.
**摘要**: 使用OR6Q1抗体阻断实验证明，该受体通过激活MAPK/ERK通路促进乳腺癌细胞迁移，提示其作为治疗靶点的潜力。
4. **文献名称**: "The role of ectopic olfactory receptors in disease: Insights from OR6Q1"
**作者**: García-Sanz, P. et al.
**摘要**: 综述OR6Q1在多种癌症中的异常表达，强调其抗体在诊断标志物开发中的应用，并讨论配体相互作用机制。
**注意**：以上为模拟示例，建议通过PubMed、Google Scholar或抗体供应商(如CiteAb)平台输入“OR6Q1 antibody”或“OR6Q1 olfactory receptor”检索真实文献。
Olfactory receptor 6Q1 (OR6Q1) is a member of the olfactory receptor (OR) family, a large group of G protein-coupled receptors (GPCRs) primarily expressed in olfactory sensory neurons. These receptors detect odorant molecules, initiating signal transduction pathways that contribute to the sense of smell. OR6Q1. encoded by the OR6Q1 gene, is classified under the OR6 subfamily and is localized on human chromosome 1. While its canonical role involves odorant detection, emerging studies suggest ectopic expression in non-olfactory tissues, such as the prostate, testis, and brain, hinting at potential non-olfactory functions in cellular signaling or disease processes.
Antibodies targeting OR6Q1 are essential tools for investigating its expression patterns, localization, and physiological roles. These antibodies are typically raised against specific epitopes, such as recombinant protein fragments or synthetic peptides corresponding to conserved regions of OR6Q1. Validation methods (e.g., Western blot, immunohistochemistry) confirm specificity, enabling researchers to study OR6Q1's distribution in tissues or its dysregulation in pathologies. Recent interest focuses on its possible involvement in cancer, including prostate cancer, where altered OR6Q1 expression may influence tumor progression or metastasis. However, functional mechanisms remain poorly understood, necessitating further research to elucidate its broader biological significance beyond olfaction.
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