| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Calcium-binding protein 7; CaBP7; |
| Entrez GeneID | 164633; |
| WB Predicted band size | 25kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from internal of human CABP7. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CABP7抗体的3篇参考文献(基于虚构内容示例，因实际文献需具体检索)：
1. **标题**：*CABP7 Expression in Neuronal Development: Insights from Immunohistochemical Analysis*
**作者**：Smith A, et al.
**摘要**：研究利用CABP7抗体探究其在哺乳动物大脑神经元分化中的表达模式，发现CABP7在小鼠海马体发育过程中动态调控钙信号通路。
2. **标题**：*Characterization of a Novel Monoclonal Antibody for CABP7 and Its Application in Cancer Biomarker Screening*
**作者**：Zhang L, et al.
**摘要**：报道一种高特异性CABP7单克隆抗体的开发，验证其在乳腺癌组织中的差异表达，提示CABP7可能作为肿瘤诊断的潜在标志物。
3. **标题**：*CABP7 Interaction with Voltage-Gated Calcium Channels Revealed by Co-Immunoprecipitation*
**作者**：Johnson R, et al.
**摘要**：通过CABP7抗体进行免疫共沉淀实验，证实其与神经元L型钙通道的相互作用，阐明其在调节钙离子稳态中的分子机制。
(注：以上为模拟示例，实际文献需通过PubMed/Google Scholar等平台检索关键词“CABP7 antibody”或“Calcium-binding protein 7”获取。)
The CABP7 (Calcium-Binding Protein 7) antibody is a tool used to detect and study the CABP7 protein, a member of the calcium-binding protein (CaBP) family. CABP7 is characterized by its EF-hand calcium-binding motifs and shares structural homology with other CaBPs like calbindin and calretinin. It is expressed in various tissues, including the brain, retina, and certain cancer cells, though its precise biological functions remain under investigation. Studies suggest CABP7 may regulate intracellular calcium signaling, which influences processes such as neuronal excitability, synaptic plasticity, and apoptosis. Its role in cancer is of particular interest, with evidence pointing to potential tumor-suppressive or oncogenic effects depending on cellular context.
The CABP7 antibody is widely utilized in research applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to map protein expression, localization, and interactions. It aids in exploring CABP7’s involvement in diseases, including neurodegenerative disorders (e.g., Alzheimer’s) and cancers. Commercial CABP7 antibodies are typically raised in rabbits or mice, with specificity validated using knockout controls. Recent studies highlight its interaction with epigenetic regulators and DNA damage response pathways, suggesting broader roles in cellular stress adaptation. Continued research with this antibody may clarify CABP7’s mechanistic contributions to health and disease.
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