| WB | 1/500-1/3000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 1/100-1/500 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | CaM kinase-like vesicle-associated protein; |
| Entrez GeneID | 79012; |
| WB Predicted band size | 54kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from internal of human CAMK5. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CAMK5抗体的模拟参考文献示例(注：内容为模拟生成，非真实文献)：
1. **文献名称**：*"CAMK5 Expression and Function in Neuronal Signal Transduction"*
**作者**：Lee, J. et al.
**摘要**：研究通过CAMK5特异性抗体揭示了其在海马神经元中的表达定位，证实CAMK5通过磷酸化下游转录因子参与突触可塑性调控。
2. **文献名称**：*"Role of CAMK5 in Cancer Cell Proliferation: An Immunohistochemical Study"*
**作者**：Chen, X. & Wang, Y.
**摘要**：利用CAMK5抗体对乳腺癌组织样本进行免疫组化分析，发现CAMK5高表达与肿瘤侵袭性正相关，提示其作为潜在治疗靶点。
3. **文献名称**：*"Validation of a Novel CAMK5 Monoclonal Antibody for Western Blot Applications"*
**作者**：Smith, R. et al.
**摘要**：报道一种高特异性CAMK5单克隆抗体的开发与验证，实验证明其在小鼠脑组织裂解液中能准确识别55 kDa的目标条带。
4. **文献名称**：*"CAMK5 Knockdown Attenuates Oxidative Stress in Cardiomyocytes: Evidence from siRNA and Antibody-based Inhibition"*
**作者**：Gupta, S. et al.
**摘要**：结合CAMK5抗体进行功能研究，发现抑制CAMK5可减少活性氧生成，改善心肌细胞在缺氧条件下的存活率。
(注：以上文献为示例，实际引用时需以真实数据库检索结果为准。)
The CAMK5 antibody is a crucial tool for studying the calcium/calmodulin-dependent protein kinase V (CAMK5 or CAMKV), a serine/threonine kinase belonging to the Ca²⁺/calmodulin-dependent kinase (CAMK) family. CAMK5 is activated by calcium signaling and calmodulin binding, playing roles in diverse cellular processes, including synaptic plasticity, gene expression, and cell cycle regulation. It is expressed in various tissues, with notable presence in the brain, where it influences neuronal development and function. Dysregulation of CAMK5 has been implicated in neurological disorders, cancer, and cardiovascular diseases, making it a target for mechanistic and therapeutic research.
CAMK5 antibodies are widely used in techniques like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry to detect protein expression, localization, and post-translational modifications. These antibodies aid in exploring CAMK5's interaction networks, phosphorylation states, and downstream signaling pathways. High-quality CAMK5 antibodies are validated for specificity, often using knockout controls, and are available as monoclonal or polyclonal forms from various host species (e.g., rabbit, mouse). Researchers rely on these reagents to investigate CAMK5's role in disease models, drug response studies, or biomarker discovery. Recent studies highlight its involvement in neuroprotection, tumor progression, and inflammation, underscoring the antibody's importance in both basic and translational research.
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