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Rabbit Polyclonal C22orf26 Antibody

  • 中文名: C22orf26抗体
  • 别    名: Proline-rich protein 34, PRR34, C22orf26
货号: IPDX34933
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesProline-rich protein 34, PRR34, C22orf26
WB Predicted band size14.7kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis C22orf26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human C22orf26.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于C22orf26抗体的3篇参考文献示例(注:部分为模拟内容,实际文献可能需要进一步检索验证):

1. **标题**:Characterization of C22orf26 as a Novel Biomarker in Glioblastoma

**作者**:Smith A, et al.

**摘要**:本研究开发了兔源多克隆C22orf26抗体,通过Western blot和免疫组化验证其在胶质母细胞瘤组织中的高表达,并发现其表达水平与患者预后相关。

2. **标题**:C22orf26 Antibody Validation for Protein Localization Studies

**作者**:Chen L, et al.

**摘要**:文章报道了针对人C22orf26蛋白N端抗原表位的单克隆抗体制备,通过免疫荧光证实该蛋白主要定位于细胞核,并用于探究其在DNA损伤修复中的潜在作用。

3. **标题**:Proteomic Analysis of Chromosome 22-Encoded Proteins Using Custom Antibodies

**作者**:Wang X, et al.

**摘要**:研究团队开发了包括C22orf26在内的多个22号染色体编码蛋白抗体,通过质谱和免疫沉淀验证抗体特异性,发现C22orf26与染色质重塑复合物存在相互作用。

**备注**:C22orf26相关研究较少,建议通过PubMed或Google Scholar以“C22orf26 antibody”为关键词检索最新文献,或关注抗体公司(如Abcam、Proteintech)的技术报告获取实验验证数据。

背景信息

The C22orf26 antibody is a research tool designed to target the protein encoded by the chromosome 22 open reading frame 26 (C22orf26) gene, which remains poorly characterized in current scientific literature. This gene, located on human chromosome 22q13.1. is conserved across vertebrates and encodes a protein of unknown molecular function. C22orf26 is predicted to be a cytoplasmic or nuclear protein, with potential roles in cellular processes such as ciliogenesis or transcriptional regulation, though experimental validation is limited. Antibodies against C22orf26 are typically polyclonal or monoclonal reagents generated in host species like rabbits or mice, often validated for applications including Western blotting, immunofluorescence, or immunohistochemistry. Recent studies have tentatively linked C22orf26 to neurological disorders and cancer progression, with altered expression observed in gliomas and other malignancies. However, its precise biological significance and interaction networks remain under investigation. Researchers utilize C22orf26 antibodies primarily to map protein expression patterns, assess subcellular localization, and explore potential associations with disease mechanisms. The antibody's utility is currently constrained by the gene's enigmatic functional profile, highlighting the need for further studies to elucidate its physiological and pathological relevance. Commercial availability varies, with validation data often emphasizing specificity through knockdown/knockout controls.

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