| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Keratin, type I cuticular Ha7, Hair keratin, type I Ha7, Keratin-37, K37, KRT37, HHA7, HKA7, KRTHA7 |
| Entrez GeneID | 8688 |
| WB Predicted band size | 49.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This KRT37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the Central region of human KRT37. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是关于KRT37抗体的3篇参考文献示例(注：文献信息为模拟生成，仅作格式参考)：
---
1. **文献名称**: *KRT37 as a novel biomarker in colorectal cancer: Immunohistochemical analysis using a novel monoclonal antibody*
**作者**: Smith, J., et al. (2020)
**摘要**: 本研究开发了一种特异性抗KRT37单克隆抗体，用于检测结直肠癌组织中KRT37的表达。研究发现，KRT37在癌变组织中的高表达与患者预后不良相关，提示其可能作为潜在的诊断标志物。
2. **文献名称**: *Keratin 37 modulates epidermal differentiation in psoriasis via antibody-mediated localization studies*
**作者**: Lee, H., & Kim, S. (2018)
**摘要**: 通过抗KRT37抗体的免疫荧光和Western blot分析，作者发现KRT37在银屑病皮损中的异常表达与表皮分化失调相关，表明其在皮肤屏障功能中的潜在作用。
3. **文献名称**: *Structural characterization of KRT37 in hair follicle development using a polyclonal antibody approach*
**作者**: García, R., et al. (2019)
**摘要**: 该研究利用多克隆抗体揭示KRT37在毛囊发育过程中的动态表达模式，证实其在毛囊角质化及形态发生中的关键功能，为脱发疾病机制提供了新见解。
---
**备注**：以上文献信息为示例性质，实际研究中请通过PubMed、Google Scholar等平台以“KRT37 antibody”“keratin 37 immunohistochemistry”等关键词检索最新文献。若需具体论文，建议补充研究领域(如癌症、皮肤病等)以便精准筛选。
The KRT37 antibody targets keratin 37 (KRT37), a member of the keratin family of intermediate filament proteins. Keratins are critical for maintaining structural integrity in epithelial cells and are classified into type I (acidic) and type II (basic) subtypes, which form heteropolymers. KRT37. a type I keratin, is primarily expressed in hair follicles, nail beds, and other specialized epithelial tissues. Its expression is tightly regulated during cellular differentiation and tissue development.
Recent studies highlight KRT37's potential role in pathological contexts, particularly cancer. Overexpression of KRT37 has been observed in certain malignancies, including squamous cell carcinomas and adenocarcinomas, suggesting its utility as a diagnostic or prognostic biomarker. The KRT37 antibody is widely used in immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting to investigate tissue-specific expression patterns, epithelial-mesenchymal transition (EMT), and tumor progression.
Additionally, KRT37 antibodies contribute to research on hair and nail disorders, given the protein’s localization in cutaneous appendages. Commercial KRT37 antibodies are typically validated for specificity across human and model organism tissues. Ongoing research explores its interactions with signaling pathways and potential therapeutic targeting in epithelial-derived diseases. Overall, the KRT37 antibody serves as a vital tool for both basic research and clinical applications in dermatology and oncology.
(Word count: 200)
×
