| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/10-1/50 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 2B11, OR2B11 |
| Entrez GeneID | 127623 |
| WB Predicted band size | 35.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR2B11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human OR2B11. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR2B11抗体的3篇参考文献示例(注：以下文献为模拟内容，实际研究可能有限，需通过专业数据库验证)：
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1. **文献名称**: *"Characterization of OR2B11 Antibody Specificity in Human Olfactory Tissue"*
**作者**: Smith A, et al.
**摘要**: 本研究开发了一种针对人类嗅觉受体OR2B11的多克隆抗体，并通过免疫组化验证其在嗅上皮组织中的特异性表达，证实OR2B11在特定嗅觉神经元亚群中的定位。
2. **文献名称**: *"OR2B11 Expression in Non-Olfactory Tissues: A Role in Immune Response"*
**作者**: Lee J, et al.
**摘要**: 利用OR2B11特异性抗体，研究发现该受体在脾脏和肠道免疫细胞中异常表达，提示其可能参与炎症信号通路的调控，为嗅觉受体在免疫系统中的功能提供新证据。
3. **文献名称**: *"Development of a Monoclonal Antibody for OR2B11 and Its Application in Cancer Biomarker Screening"*
**作者**: Chen X, et al.
**摘要**: 通过杂交瘤技术制备了高亲和力OR2B11单克隆抗体，并应用于肺癌组织芯片分析，发现OR2B11在部分肿瘤细胞中高表达，可能作为潜在诊断标志物。
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**注意**：以上文献为示例，OR2B11相关研究较少，实际文献需通过PubMed或Google Scholar检索关键词(如“OR2B11 antibody”、“olfactory receptor antibody”)获取。部分研究可能侧重基因功能而非抗体开发，建议结合具体需求筛选。
The OR2B11 antibody is a research tool designed to target the olfactory receptor family 2. subfamily B, member 11 (OR2B11), a G protein-coupled receptor (GPCR) primarily associated with olfactory signaling. Olfactory receptors (ORs) are traditionally known for their role in detecting odorants in the nasal epithelium, but emerging studies reveal their expression in non-olfactory tissues, including the prostate, lungs, and brain, suggesting broader physiological functions. OR2B11. in particular, has been implicated in cellular processes like migration, inflammation, and possibly cancer progression, though its precise mechanisms remain under investigation.
Antibodies against OR2B11 are used to study its localization, expression patterns, and functional roles in both olfactory and ectopic tissues. Due to the structural complexity of ORs (seven-transmembrane domains) and low antigenicity, developing specific antibodies for OR2B11 is challenging. Commercial antibodies are typically validated via Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF), often paired with knockout controls to confirm specificity.
Research utilizing OR2B11 antibodies has explored its potential involvement in diseases such as prostate cancer, where altered expression may correlate with tumorigenesis, or in inflammatory responses linked to respiratory conditions. However, data remain preliminary, and further studies are needed to clarify its pathophysiological relevance. Overall, OR2B11 antibodies serve as critical tools for decoding the expanding roles of olfactory receptors beyond smell, bridging gaps between chemosensation and systemic biology.
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