Rabbit Polyclonal OR1J4 Antibody

The OR1J4 antibody is a specialized tool used to detect and study the olfactory receptor family 1. subfamily J, member 4 (OR1J4), a G protein-coupled receptor (GPCR) primarily associated with olfactory sensory neurons. Olfactory receptors, including OR1J4. play a critical role in detecting odorant molecules and initiating signal transduction pathways that contribute to the sense of smell. While OR1J4 is predominantly expressed in olfactory tissues, emerging research suggests its ectopic expression in non-olfactory tissues, such as the prostate, liver, and certain cancers, hinting at potential roles in cellular processes beyond chemosensation. The OR1J4 antibody is commonly utilized in techniques like Western blotting, immunohistochemistry, and ELISA to investigate its expression patterns, localization, and functional interactions. Studies leveraging this antibody have explored OR1J4’s involvement in disease contexts, including cancer progression and metabolic disorders, where its dysregulation may serve as a biomarker or therapeutic target. Additionally, structural analyses using the antibody contribute to understanding OR1J4’s ligand-binding specificity and activation mechanisms, offering insights into GPCR signaling diversity. Despite its niche focus, OR1J4 remains a valuable model for probing olfactory receptor biology and their unexpected roles in human physiology and pathology.