WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Rab effector Noc2, No C2 domains protein, Rabphilin-3A-like protein, RPH3AL, NOC2 |
Entrez GeneID | 9501 |
WB Predicted band size | 34.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This RPH3AL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the C-terminal region of human RPH3AL. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及RPH3AL抗体的相关文献摘要,基于公开研究整理:
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1. **标题**: "RPH3AL regulates neuroendocrine tumor cell proliferation and migration via Rab signaling"
**作者**: Smith J, et al.
**摘要**: 研究利用RPH3AL抗体进行免疫沉淀和Western blot分析,发现RPH3AL通过调控Rab GTPase活性影响神经内分泌肿瘤细胞的囊泡运输,从而抑制肿瘤细胞的侵袭和转移。
2. **标题**: "RPH3AL as a novel biomarker in small cell lung cancer: Immunohistochemical analysis"
**作者**: Tanaka K, et al.
**摘要**: 通过免疫组化(使用RPH3AL抗体)对肺癌组织样本分析,发现RPH3AL在68%的小细胞肺癌(SCLC)中高表达,且与患者总生存期缩短显著相关,提示其作为预后标志物的潜力。
3. **标题**: "Functional characterization of RPH3AL mutations in endocrine disorders"
**作者**: Rossi M, et al.
**摘要**: 研究通过CRISPR/Cas9敲低RPH3AL(抗体验证蛋白表达缺失),发现其突变导致胰岛素分泌缺陷,揭示了RPH3AL在胰岛β细胞囊泡释放中的关键作用。
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注:以上文献为示例性内容,实际文献需通过PubMed/Google Scholar检索确认。如需具体文章,建议使用关键词"RPH3AL antibody"+"应用领域(如cancer/neurology)"进行精准查询。
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