Rabbit Polyclonal VKORC1L1(N-term) Antibody

The VKORC1L1 (N-term) antibody is designed to target the N-terminal region of the VKORC1-like protein 1 (VKORC1L1), a member of the vitamin K epoxide reductase (VKOR) family. VKORC1L1 shares structural homology with VKORC1. a key enzyme in the vitamin K cycle responsible for regenerating reduced vitamin K, which is essential for γ-carboxylation of coagulation factors and other vitamin K-dependent proteins. While VKORC1 is primarily associated with blood coagulation, VKORC1L1 is implicated in alternative redox pathways, potentially influencing cellular antioxidant mechanisms and mitochondrial function. Its precise biological roles remain under investigation, though studies suggest links to cancer, cardiovascular diseases, and metabolic disorders. The VKORC1L1 (N-term) antibody serves as a critical tool for detecting and quantifying the protein in experimental models, enabling researchers to explore its expression patterns, subcellular localization, and interaction partners. Validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, this antibody aids in elucidating VKORC1L1’s physiological and pathological significance, particularly its divergence from VKORC1 in tissue-specific functions and disease pathways. Ongoing research aims to clarify its regulatory mechanisms and therapeutic potential.