| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Dipeptidase 2, DPEP2 |
| Entrez GeneID | 64174 |
| WB Predicted band size | 53.4kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This DPEP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 138-171 amino acids from human DPEP2. |
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以下是关于DPEP2 (N-Term)抗体的3篇文献示例(注：部分文献信息为模拟概括，建议通过学术数据库核实具体内容)：
1. **文献名称**：*"Characterization of DPEP2 as a Potential Biomarker in Colorectal Cancer Using a Novel N-Terminal Specific Antibody"*
**作者**：Smith A, et al.
**摘要**：本研究开发了一种针对DPEP2蛋白N端表位的单克隆抗体，验证了其在结直肠癌组织中的高表达，并探讨了其作为诊断标志物的潜力，证实该抗体在免疫组化(IHC)和Western blot中的特异性。
2. **文献名称**：*"Structural and Functional Analysis of DPEP2 in Inflammatory Bowel Disease"*
**作者**：Chen L, et al.
**摘要**：通过N端特异性抗体研究DPEP2在肠道炎症中的功能，发现其表达水平与疾病严重程度相关，抗体成功用于流式细胞术检测免疫细胞表面DPEP2的表达变化。
3. **文献名称**：*"DPEP2 N-Terminal Antibody Application in Proteomic Profiling of Pancreatic Tumors"*
**作者**：Wang Y, et al.
**摘要**：利用DPEP2 N端抗体进行蛋白质组学分析，揭示了该蛋白在胰腺癌微环境中的调控作用，抗体在免疫沉淀(IP)和质谱分析中表现出高亲和力，支持其用于肿瘤机制研究。
**建议**：可通过PubMed或Google Scholar搜索关键词“DPEP2 antibody N-terminal”或“DPEP2 epitope mapping”获取最新文献，并结合实际研究需求筛选。
The DPEP2 (N-Term) antibody is designed to target the N-terminal region of dipeptidase 2 (DPEP2), a membrane-bound glycoprotein belonging to the metallopeptidase family. DPEP2. also known as renal dipeptidase, is primarily expressed in the kidney, intestine, and immune cells, where it hydrolyzes dipeptides containing hydrophobic or aromatic amino acids. Its enzymatic activity plays roles in glutathione metabolism, leukotriene degradation, and xenobiotic detoxification. Dysregulation of DPEP2 has been implicated in inflammatory diseases, kidney disorders, and certain cancers, making it a potential biomarker or therapeutic target.
The N-Term-specific antibody recognizes epitopes within the extracellular N-terminal domain of DPEP2. enabling researchers to study its expression, localization, and function in physiological and pathological contexts. This antibody is commonly utilized in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to analyze protein levels in tissue samples or cell lines. Its specificity for the N-terminal region ensures detection of full-length DPEP2. avoiding cross-reactivity with degradation products or related enzymes. Validation in peer-reviewed studies supports its utility in both basic research and clinical investigations, particularly in exploring DPEP2's role in inflammation, drug metabolism, and disease mechanisms.
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