Rabbit Polyclonal (DANRE)hbae1 Antibody

The DANRE (Danio rerio, zebrafish) hbae1 antibody targets the hemoglobin alpha embryonic 1 (hbae1) protein, a key component of embryonic hemoglobin in zebrafish. Hbae1 is expressed during early developmental stages, primarily in erythroid cells, and plays a critical role in oxygen transport during embryogenesis. Zebrafish, a widely used vertebrate model for developmental biology and hematopoiesis studies, relies on embryonic hemoglobins like Hbae1 to support rapid growth and tissue oxygenation before the adult circulatory system matures. The hbae1 antibody is typically generated in hosts like rabbits or mice using immunogenic peptides or recombinant proteins specific to the zebrafish hbae1 sequence. It is employed in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to visualize spatial-temporal expression patterns, study erythrocyte development, or investigate genetic or environmental disruptions in hemoglobin production. This antibody has been instrumental in modeling human blood disorders (e.g., anemia) and understanding conserved molecular mechanisms of vertebrate hematopoiesis. Its specificity for zebrafish hbae1 ensures minimal cross-reactivity with adult hemoglobin isoforms, making it a valuable tool for developmental-stage-specific research.