Rabbit Polyclonal (DANRE)slc17a6a Antibody

The DANRE (zebrafish, *Danio rerio*) slc17a6a antibody targets the solute carrier family 17 member 6a protein, a homolog of mammalian vesicular glutamate transporter 2 (VGLUT2). SLC17A6a facilitates the uptake of glutamate into synaptic vesicles, enabling excitatory neurotransmission. In zebrafish, this transporter is critical for glutamatergic signaling in the central nervous system, particularly in regions involved in sensory processing, motor coordination, and behavioral responses. The slc17a6a antibody is widely used to label glutamatergic neurons and map their projections in neurodevelopmental studies, given zebrafish’s transparency and genetic tractability. Researchers employ it in immunohistochemistry, whole-mount in situ hybridization validations, and protein localization assays to investigate neural circuit assembly, synaptic plasticity, or disease models (e.g., neurodegeneration, epilepsy). Its specificity for zebrafish SLC17A6a makes it valuable for distinguishing glutamatergic populations from other neurotransmitter systems. Recent studies also utilize this antibody to explore how glutamate dysregulation contributes to behavioral phenotypes or environmental toxin responses. By enabling precise visualization of glutamatergic pathways, the antibody supports mechanistic insights into brain function and dysfunction in a vertebrate model amenable to high-throughput screening.