| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 610, ZNF610 |
| Entrez GeneID | 162963 |
| WB Predicted band size | 53.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZNF610 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 433-468 amino acids from the C-terminal region of human ZNF610. |
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以下是关于ZNF610抗体的3篇虚构参考文献示例(仅供参考，实际文献需通过学术数据库查询)：
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1. **文献名称**: "ZNF610 modulates DNA repair pathways via interaction with PARP1"
**作者**: Chen, L., et al.
**摘要**: 本研究利用ZNF610特异性抗体进行免疫共沉淀(Co-IP)实验，发现ZNF610与PARP1蛋白在DNA损伤应答中直接相互作用，调控同源重组修复通路，可能影响癌症化疗耐药性。
2. **文献名称**: "Dysregulation of ZNF610 in Alzheimer's disease patient brains"
**作者**: Smith, J.R., et al.
**摘要**: 通过免疫组化(IHC)和Western blot分析，作者发现ZNF610蛋白在阿尔茨海默病患者脑组织中表达显著下调，提示其可能参与神经退行性病变中的表观遗传调控。
3. **文献名称**: "ZNF610 antibody validation for chromatin immunoprecipitation sequencing (ChIP-seq)"
**作者**: Wang, Y., et al.
**摘要**: 该文献系统验证了商用ZNF610抗体的特异性，通过敲除细胞系对比和质谱分析，确认其适用于ChIP-seq研究，并揭示了ZNF610在基因组中富集于转座子元件区域。
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如需真实文献，建议访问 **PubMed** 或 **Google Scholar**，搜索关键词“ZNF610 antibody”或“ZNF610 function”。部分文献可能侧重于抗体制备、验证或其在特定疾病模型中的应用。
The ZNF610 antibody is a research tool designed to detect the zinc finger protein 610 (ZNF610), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein (ZNF) family. ZNF610 is encoded by the human *ZNF610* gene located on chromosome 19q13.43. As a transcription factor, it is hypothesized to regulate gene expression by binding DNA through its C2H2-type zinc finger motifs, potentially influencing cellular processes such as differentiation, apoptosis, or epigenetic modulation. However, the precise biological functions of ZNF610 remain poorly characterized compared to other ZNF proteins.
Commercial ZNF610 antibodies are typically polyclonal or monoclonal antibodies raised in rabbits or mice, targeting specific epitopes within the protein’s N-terminal, KRAB domain, or zinc finger regions. These antibodies are validated for applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study ZNF610 expression patterns in tissues or cultured cells. Research involving ZNF610 antibodies has explored its potential roles in diseases, including cancer (e.g., aberrant expression in gliomas or colorectal cancer) and neurological disorders, though mechanistic insights are limited.
Current challenges include the need for stricter validation of antibody specificity, given high homology among ZNF family members, and further functional studies to clarify ZNF610’s interaction networks and downstream targets. Its involvement in pathways like TGF-β signaling or retroelement suppression remains an active area of investigation.
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