Rabbit Polyclonal RSF1 Antibody

The RSF1 (Remodeling and Spacing Factor 1) antibody is a tool used to detect RSF1. a chromatin-remodeling protein critical for maintaining genome stability and regulating gene expression. RSF1 forms the RSF complex with the ATPase subunit SNF2H (SNF2 histone linker PHD RING helicase), which facilitates nucleosome repositioning and chromatin compaction. This complex plays roles in DNA repair, replication, and transcriptional regulation. Dysregulation of RSF1 is linked to cancer progression, as its overexpression is observed in ovarian, hepatocellular, and gastric cancers, correlating with poor prognosis. The RSF1 antibody is widely used in research to investigate its biological functions, including chromatin dynamics, epigenetic modifications, and cancer mechanisms. It is applied in techniques like Western blotting, immunofluorescence, immunohistochemistry, and co-immunoprecipitation to assess RSF1 expression, localization, and interactions. Studies also utilize this antibody to explore RSF1's potential as a therapeutic target or diagnostic biomarker. Its specificity and reliability make it essential for elucidating RSF1's role in cellular processes and disease contexts, particularly in oncology and epigenetics research.