WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Zinc finger protein 560, ZNF560 |
Entrez GeneID | 147741 |
WB Predicted band size | 91.1kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This ZNF560 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-325 amino acids from the Central region of human ZNF560. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZNF560抗体的模拟参考文献(注:部分文献为假设性示例,建议通过学术数据库核实具体信息):
1. **文献名称**: "ZNF560 modulates transcriptional regulation in hepatocellular carcinoma via antibody-specific chromatin immunoprecipitation"
**作者**: Liu, X. et al. (2021)
**摘要**: 本研究利用ZNF560抗体进行ChIP-seq实验,揭示其在肝癌细胞中结合特定DNA启动子区域,调控致癌基因表达的功能。
2. **文献名称**: "Development and validation of a polyclonal antibody against human ZNF560 for immunohistochemical analysis"
**作者**: Tanaka, K. et al. (2019)
**摘要**: 报道了一种新型ZNF560多克隆抗体的开发,验证其在人组织切片中的特异性,并用于检测ZNF560在正常与肿瘤组织中的差异表达。
3. **文献名称**: "ZNF560 interacts with p53 pathway: Evidence from co-immunoprecipitation using specific antibodies"
**作者**: Gupta, R. & Lee, S. (2020)
**摘要**: 通过ZNF560抗体的免疫共沉淀实验,证明其与p53蛋白的相互作用,提示其在DNA损伤应答中的潜在调控机制。
4. **文献名称**: "Antibody-based screening identifies ZNF560 as a novel biomarker in colorectal cancer progression"
**作者**: Martínez, E. et al. (2022)
**摘要**: 利用ZNF560抗体进行高通量蛋白质组学筛选,发现其在结直肠癌转移阶段表达显著上调,可能作为预后标志物。
**注意**:以上文献为模拟生成,实际研究中ZNF560相关抗体文献可能较少,建议结合PubMed、Web of Science等平台以“ZNF560 antibody”为关键词检索最新进展。
The ZNF560 antibody is a research tool designed to detect and study zinc finger protein 560 (ZNF560), a member of the zinc finger protein family characterized by conserved C2H2-type zinc finger motifs. These proteins typically function as transcription factors, binding DNA or interacting with other proteins to regulate gene expression. While the specific biological roles of ZNF560 remain under investigation, it is hypothesized to participate in cellular processes such as differentiation, apoptosis, or chromatin remodeling, given the functional diversity of zinc finger proteins.
Developed for experimental applications like Western blotting, immunoprecipitation, and immunofluorescence, the ZNF560 antibody is commonly raised in host species like rabbits or mice. Its specificity is validated using knockout controls or epitope-mapping techniques to ensure recognition of conserved regions within the ZNF560 protein. Studies utilizing this antibody aim to elucidate ZNF560's expression patterns across tissues, its subcellular localization, and potential involvement in diseases, including cancer or developmental disorders.
Current research focuses on identifying ZNF560's target genes, interaction partners, and regulatory mechanisms. However, limited literature directly links ZNF560 to specific pathways, highlighting the need for further exploration. Researchers employ this antibody to advance understanding of zinc finger protein biology and its implications in health and disease. Commercial suppliers typically provide detailed validation data to ensure reproducibility in experimental settings.
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