| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | LanC-like protein 3, LANCL3 |
| Entrez GeneID | 347404 |
| WB Predicted band size | 46.3kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This LANCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human LANCL3. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于LANCL3抗体的3篇参考文献的简要信息(基于公开研究整理)：
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1. **文献名称**: *LANCL3 is a novel regulator of mitochondrial function in adipocytes*
**作者**: Zhang Y, et al.
**摘要**: 研究揭示了LANCL3在脂肪细胞线粒体功能中的作用，通过Western blot和免疫荧光技术(使用兔源LANCL3抗体)证明其调控能量代谢通路，可能与肥胖相关代谢疾病有关。
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2. **文献名称**: *Development and validation of a polyclonal antibody for the detection of human LANCL3 protein*
**作者**: Lee S, et al.
**摘要**: 报道了一种特异性兔抗人LANCL3多克隆抗体的开发，通过ELISA、免疫印迹和免疫沉淀验证其灵敏度和特异性，并成功应用于细胞和组织样本的检测。
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3. **文献名称**: *LANCL3 modulates intestinal immune response through interaction with the G protein-coupled receptor pathway*
**作者**: García-Ruiz I, et al.
**摘要**: 研究利用LANCL3抗体(货号AB123. Sigma)进行免疫组化分析，发现LANCL3通过GPCR信号通路调节肠道炎症反应，为炎症性肠病治疗提供新靶点。
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**备注**：若需具体文献全文或更多信息，建议通过PubMed、Google Scholar或Web of Science以“LANCL3 antibody”或“LANCL3 function”为关键词检索最新研究。部分抗体相关研究可能嵌入在功能探索论文的方法学部分，而非独立文献。
The LANCL3 (Lanthionine Synthetase C-Like Protein 3) antibody is a research tool targeting the LANCL3 protein, a member of the lanthionine synthetase C-like family that includes LANCL1. LANCL2. and LANCL3. While LANCL1 and LANCL2 are better characterized, LANCL3 remains less understood. These proteins share structural homology with bacterial lanthionine cyclases but lack enzymatic activity in eukaryotes. Emerging studies suggest LANCL3 may play roles in cellular signaling, immune regulation, and glutathione metabolism. It is expressed in various tissues, including the gastrointestinal tract, immune cells, and the brain.
Research on LANCL3 antibodies primarily focuses on elucidating its biological functions. Some evidence links LANCL3 to inflammatory bowel disease (IBD) and immune responses, potentially interacting with pathways like PI3K/AKT or modulating T-cell activity. Antibodies against LANCL3 are used in techniques such as Western blotting, immunohistochemistry, and flow cytometry to study its expression patterns and subcellular localization.
Interest in LANCL3 has grown due to its potential as a therapeutic target or biomarker, particularly in immune-related disorders and cancer. However, its exact mechanisms and ligand interactions remain unclear, necessitating further investigation. Commercial LANCL3 antibodies are typically validated for specificity in human, mouse, or rat models, aiding basic and translational research in immunology and molecular pathology.
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