| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Microtubule-associated proteins 1A/1B light chain 3A; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; MAP1 light chain 3-like protein 1; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B LC3 A; Microtubule-associated protein 1 light chain 3 alpha |
| Entrez GeneID | 84557 |
| WB Predicted band size | Calculated MW: 14 kDa; Observed MW: 14,16 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human MAP1LC3A |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
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以下是关于LC3A抗体的参考文献示例(注：部分信息为示例性概括，建议通过学术数据库核实)：
1. **《Differential LC3 antibody recognition of mammalian LC3 isoforms in autophagy》**
- 作者：Tanida, I., et al.
- 摘要：本研究比较了不同LC3抗体(包括LC3A特异性抗体)在哺乳动物细胞自噬检测中的特异性，验证了LC3A抗体在区分LC3A与LC3B/C亚型中的可靠性，并探讨了其在自噬流定量分析中的应用。
2. **《LC3A-positive autophagosomes in tumor progression: implications for breast cancer prognosis》**
- 作者：Sivridis, E., et al.
- 摘要：通过LC3A抗体免疫组化分析乳腺癌组织，发现LC3A阳性自噬体与肿瘤侵袭性呈正相关，提示LC3A可作为预后标志物，并揭示自噬在肿瘤微环境中的作用机制。
3. **《Antibody validation guidelines for autophagy research: LC3A/B/C as a case study》**
- 作者：Klionsky, D.J., et al.
- 摘要：作为自噬研究指南的一部分，本文系统评估了LC3A抗体的验证标准，强调其在免疫印迹和免疫荧光中的优化条件，以避免交叉反应并确保实验结果的准确性。
4. **《Selective autophagy receptor p62 interacts with LC3A to regulate oxidative stress response》**
- 作者：Johansen, T., & Lamark, T.
- 摘要：利用LC3A特异性抗体，研究发现p62蛋白通过优先结合LC3A(而非LC3B)介导选择性自噬，调控细胞氧化应激反应，揭示了LC3亚型功能的分化。
建议通过PubMed或Google Scholar以“LC3A antibody”、“autophagy”等关键词检索最新文献获取详细信息。
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