Cat: IPD-X39005

Recombinant Human BNC2 Protein,His

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关键信息

  • 基因名

    BNC2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    BSN2; Zinc finger protein basonuclin-2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6ZN30

  • 表达区间

    Thr941~Asp1099

  • 分子量

    30kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

BNC2, or Basonuclin 2, is a transcription factor that plays a crucial role in various biological processes, including cellular differentiation, proliferation, and embryonic development. Originally identified in the context of germ cell development and spermatogenesis, BNC2 has garnered attention for its potential implications in both normal physiology and pathological conditions such as cancer and infertility. Its expression is notably observed in the testis and in specific tissues where it may regulate key genes involved in maintaining stem cell properties and promoting differentiation. Recent studies have aimed to elucidate the molecular mechanisms by which BNC2 exerts its effects and to explore its interactions with other signaling pathways. The recombinant expression of BNC2 protein allows researchers to investigate its functional properties in vitro and in vivo, facilitating the understanding of its role in gene regulation. Furthermore, the development of BNC2 as a biomarker in certain malignancies could provide insights into tumor biology and aid in the discovery of novel therapeutic strategies. By creating a recombinant BNC2 protein, researchers aim to enhance their understanding of its structural and functional characteristics, paving the way for potential applications in regenerative medicine and cancer therapy. The comprehensive study of BNC2 not only contributes to the fundamental knowledge of transcriptional regulation but also highlights its significance as a target for therapeutic intervention in various diseases.

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