关键信息
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基因名
C14orf166
- 应用
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别名
CLE7 homolog
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y224
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表达区间
1-244aa
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分子量
55.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
C14orf166, also known as LGR5, is a gene located on chromosome 14, which encodes a protein involved in several critical biological processes, including cell proliferation, differentiation, and tissue regeneration. Research indicates that C14orf166 plays a significant role in stem cell maintenance and renewal, particularly in the context of various cancers and developmental disorders. The investigation of C14orf166 recombinant protein has gained momentum due to its potential implications in regenerative medicine and oncology. Studies have revealed that this protein is implicated in key signaling pathways, such as Wnt and Notch, which are essential for maintaining the balance between cell growth and apoptosis. Furthermore, dysregulation of C14orf166 expression has been associated with tumorigenesis, making it a potential biomarker for cancer diagnosis and prognosis, as well as a target for therapeutic interventions. The production and characterization of C14orf166 recombinant protein can provide valuable insights into its functional roles and mechanisms, facilitating the development of novel treatment strategies. This research avenue holds promise for uncovering new therapeutic targets and advancing our understanding of the molecular underpinnings of diseases linked to C14orf166 dysregulation.
