| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | AN11; Dcaf7; HAN11; WDR68;;DCAF7 |
| WB Predicted band size | 39 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human DCAF7 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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1. **文献名称**：DCAF7 regulates Wnt signaling by maintaining the stability of Dishevelled
**作者**：Sato, A., et al.
**摘要**：该研究揭示了DCAF7通过结合Dishevelled(DVL)蛋白，调控Wnt/β-catenin信号通路的活性。DCAF7的缺失导致DVL蛋白泛素化降解，从而抑制Wnt信号传导，影响胚胎发育和癌症进展。研究通过免疫共沉淀和Western blot验证了DCAF7抗体的特异性。
2. **文献名称**：DCAF7 as a potential biomarker in head and neck squamous cell carcinoma
**作者**：Lee, J., et al.
**摘要**：研究发现DCAF7在头颈鳞癌组织中高表达，与患者不良预后相关。通过免疫组化和免疫荧光实验(使用DCAF7抗体)证实其与肿瘤增殖和转移的关系，并提示其可能作为治疗靶点。
3. **文献名称**：Functional interaction between DCAF7 and CUL4-DDB1 ubiquitin ligase in cell cycle regulation
**作者**：Zhang, Y., et al.
**摘要**：该研究阐明DCAF7作为CUL4-DDB1泛素连接酶复合体的适配蛋白，参与细胞周期调控。通过RNA干扰和抗体介导的蛋白互作分析，发现DCAF7缺失导致细胞周期停滞，提示其在肿瘤发生中的关键作用。
4. **文献名称**：DCAF7 is essential for craniofacial development via modulating BMP signaling
**作者**：Wang, H., et al.
**摘要**：利用斑马鱼模型和DCAF7抗体进行蛋白定位研究，发现DCAF7通过调控BMP信号通路影响颅面发育。DCAF7缺失导致胚胎颅骨畸形，揭示其在发育生物学中的新功能。
(注：以上文献为示例，实际引用需以真实发表的论文为准。)
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