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Rabbit Monoclonal RPL7A Antibody

  • 中文名： RPL7A抗体
  • 别    名： PLA X polypeptide; RP23-414L19.4; RPL7A; SURF3; surfeit 3; TRUP;;RPL7A
货号: IPDX18815
Price： ￥1280
数量：
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/200 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesPLA X polypeptide; RP23-414L19.4; RPL7A; SURF3; surfeit 3; TRUP;;RPL7A
WB Predicted band size30 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human RPL7A
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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参考文献

以下是关于RPL7A抗体的3篇参考文献示例(注：以下内容为虚构示例，实际文献需通过学术数据库检索)：

1. **文献名称**：*"RPL7A Expression in Leukemia: A Potential Diagnostic Marker"*

**作者**：Smith J, et al. (2018)

**摘要**：研究通过Western blot和免疫荧光技术，利用RPL7A抗体检测白血病细胞中RPL7A蛋白的过表达，发现其与疾病进展相关，提示其可能作为白血病诊断标志物。

2. **文献名称**：*"Role of RPL7A in Ribosome Biogenesis and Zebrafish Development"*

**作者**：Johnson R, et al. (2016)

**摘要**：通过免疫组化(IHC)和免疫沉淀(IP)技术结合RPL7A抗体，揭示了RPL7A在核糖体组装中的关键作用，并发现其缺失导致斑马鱼胚胎发育异常。

3. **文献名称**：*"Interaction of RPL7A with HIV-1 Viral Proteins"*

**作者**：Lee S, et al. (2020)

**摘要**：研究使用RPL7A抗体进行免疫共沉淀(Co-IP)和质谱分析，发现RPL7A与HIV-1病毒蛋白直接互作，可能调控病毒复制过程。

如需真实文献，建议通过PubMed或Google Scholar搜索关键词“RPL7A antibody”或“RPL7A protein function”。

背景信息

The RPL7A antibody targets the ribosomal protein L7A, a component of the 60S ribosomal subunit involved in protein synthesis. Encoded by the *RPL7A* gene (located on chromosome 19q13.2 in humans), this highly conserved protein plays dual roles in ribosome assembly and extraribosomal functions, including potential involvement in cell cycle regulation, apoptosis, and interactions with RNA or other proteins like p53. RPL7A is ubiquitously expressed across tissues, reflecting its essential role in cellular homeostasis. Antibodies against RPL7A are widely used in research to study its expression, localization, and interactions in normal and disease contexts, such as cancer, where ribosomal proteins may exhibit dysregulated expression. These antibodies are validated for techniques like Western blotting, immunofluorescence, and immunoprecipitation, often with cross-reactivity in common model organisms (e.g., mice, rats). Studies using RPL7A antibodies have also explored its potential as a biomarker or therapeutic target, given its links to tumor progression and chemoresistance. Proper validation, including knockdown controls and species specificity checks, is critical due to its homology with other ribosomal proteins.

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