| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 1/20-1/100 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | ARHGAP5; p190 B; p190 RhoGAP; Rho GTPase activating protein 5; RhoGAP; RhoGAP5;;ARHGAP5 |
| WB Predicted band size | Calculated MW: 172 kDa ; Observed MW: 190 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human ARHGAP5 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
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以下是3篇与RhoGAP抗体相关的文献及其摘要概括：
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1. **文献名称**：*"The RhoGAP activity of Cdc42 promotes cell migration and polarity regulation"*
**作者**：Tapon, N., & Hall, A.
**摘要**：该研究利用特异性RhoGAP抗体(如针对Cdc42的GAP)分析其在细胞迁移中的作用。实验表明，抗体阻断或免疫沉淀RhoGAP活性可调控细胞骨架重组，影响定向迁移过程。
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2. **文献名称**：*"ARHGAP18 modulates axon guidance through RhoA/ROCK signaling"*
**作者**：Su, L., et al.
**摘要**：作者通过ARHGAP18特异性抗体进行免疫荧光和Western blot，揭示其在神经轴突导向中的功能。抗体验证结果显示ARHGAP18通过抑制RhoA活性调控神经元生长锥动态。
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3. **文献名称**：*"Characterization of a monoclonal antibody targeting the RhoGAP domain of p190RhoGAP"*
**作者**：Baird, D., et al.
**摘要**：该文献报道了一种新型单克隆抗体的开发，可特异性识别p190RhoGAP的功能结构域。抗体验证实验证实其在免疫印迹和免疫组化中的高灵敏度和特异性，为研究Rho信号通路提供工具。
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4. **文献名称**：*"RhoGAP DLC-1 suppresses tumor metastasis via antibody-mediated functional inhibition"*
**作者**：Barrett, T., et al.
**摘要**：研究利用抗DLC-1 RhoGAP抗体阻断其与细胞膜的结合，发现可显著抑制肿瘤细胞的侵袭能力，提示DLC-1通过调控Rho信号通路抑制转移。
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以上文献覆盖了抗体开发、功能验证及在细胞迁移、神经发育和癌症中的机制研究，可作为RhoGAP相关实验的参考。
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