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Rabbit Monoclonal HIPK2 Antibody

  • 中文名： HIPK2抗体
  • 别    名： hHIPk2; Hipk2; Nbak1; Stank;;HIPK2
货号: IPDX18326
Price： ￥1280
数量：
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验证与应用

应用及物种
WB 1/1000-1/2000 Human,Mouse,Rat
IF 1/20-1/50 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 1/50-1/200 Human,Mouse,Rat
FCM 1/20-1/100 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliaseshHIPk2; Hipk2; Nbak1; Stank;;HIPK2
WB Predicted band sizeCalculated MW: 131 kDa ; Observed MW: 130,100 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse
ImmunogenA synthesized peptide derived from human HIPK2
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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参考文献

以下是3篇关于HIPK2抗体的模拟参考文献示例(实际文献请通过学术数据库检索)：

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1. **文献名称**: *HIPK2 modulates p53-dependent apoptosis through kinase activity regulation*

**作者**: Rinaldo C, et al.

**摘要**: 本研究利用特异性HIPK2抗体，通过免疫沉淀和Western blot技术揭示了HIPK2在DNA损伤条件下通过磷酸化p53调控细胞凋亡的分子机制，证明其激酶活性对肿瘤抑制功能至关重要。

2. **文献名称**: *Development of a monoclonal antibody targeting the Ser486 phosphorylation site of HIPK2*

**作者**: Tanaka Y, et al.

**摘要**: 文章报道了一种针对HIPK2 Ser486磷酸化位点的高效单克隆抗体的开发与验证，该抗体可用于免疫荧光和流式细胞术，为研究HIPK2在细胞周期中的动态修饰提供了工具。

3. **文献名称**: *HIPK2 suppression promotes tumor progression in colorectal cancer*

**作者**: Wang L, et al.

**摘要**: 通过免疫组化(使用商业化HIPK2抗体)分析结直肠癌组织样本，发现HIPK2低表达与患者预后不良相关，并验证了其通过Wnt/β-catenin通路抑制肿瘤转移的功能。

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**备注**：以上为模拟文献，真实文献建议通过PubMed(https://pubmed.ncbi.nlm.nih.gov)或Google Scholar检索关键词如“HIPK2 antibody”、“HIPK2 kinase function”等。实际研究多涉及HIPK2在凋亡、癌症、神经退行性疾病中的机制及抗体应用。

背景信息

HIPAA (Health Insurance Portability and Accountability Act) is a U.S. federal law enacted in 1996 to establish national standards for protecting sensitive patient health information. Prior to HIPAA, there was no comprehensive federal regulation governing the privacy and security of medical records, leading to variability in practices across states and healthcare entities. The law consists of two main components: the Privacy Rule and the Security Rule. The Privacy Rule, implemented in 2003. sets limits on the use and disclosure of protected health information (PHI) without patient authorization, while the Security Rule (2005) outlines safeguards for electronic PHI. HIPAA also includes provisions for healthcare portability, ensuring individuals can maintain insurance coverage when changing jobs. Compliance is enforced by the Department of Health and Human Services, with penalties for violations ranging from fines to criminal charges. The law has significantly influenced healthcare operations, requiring organizations to implement administrative, physical, and technical protections. However, challenges remain in adapting to evolving technologies like telehealth and cloud storage while maintaining compliance. HIPAA's impact extends beyond healthcare providers to include business associates, health plans, and healthcare clearinghouses that handle PHI.

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