| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | ZNF595 |
| Uniprot No | Q8IYB9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-648 aa |
| 活性数据 | MELVTFRDVAIEFSPEEWKCLDPAQQNLYRDVMLENYRNLVSLGFVISNPDLVTCLEQIKEPCNLKIHETAAKPPAICSPFSQDLSPVQGIEDSFHKLILKRYEKCGHENLQLRKGCKRVNECKVQKGVNNGVYQCLSTTQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYMSHLTQHTGIHAGEKPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRSIHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGKAFNRPSTLTVHKRIHTGKEHS |
| 分子量 | 97.68 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是3篇关于重组人ZNF595蛋白的示例文献(注：实际文献请通过专业数据库验证，以下内容为示例性概括)：
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1. **Title**: *"Structural characterization and DNA-binding properties of recombinant human ZNF595 protein"*
**Authors**: Chen L., Wang H., et al.
**Summary**: 本研究通过原核表达系统纯化重组人ZNF595蛋白，解析其锌指结构域与特定DNA序列结合的能力，证实其在基因转录调控中的潜在作用。
2. **Title**: *"ZNF595 overexpression modulates neural differentiation in vitro via epigenetic regulation"*
**Authors**: Kim S., Takahashi N., et al.
**Summary**: 通过体外实验发现，重组ZNF595蛋白能通过HDAC复合物调控组蛋白乙酰化，影响神经干细胞分化，提示其在神经发育疾病中的病理关联。
3. **Title**: *"Functional screening of ZNF595 interactions in cancer cell proliferation"*
**Authors**: Rodriguez A., Martinez R., et al.
**Summary**: 研究发现重组ZNF595在多种癌细胞系中异常表达，并通过干扰Wnt/β-catenin信号通路抑制肿瘤细胞增殖，提出其作为潜在治疗靶点的可能性。
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**提示**：建议通过PubMed或Google Scholar输入关键词"ZNF595 recombinant protein"或"human ZNF595 function"检索真实文献。若需实际引用，请核实文献准确性与数据库收录状态。
ZNF595. a member of the zinc finger protein family, is a human transcription factor encoded by the *ZNF595* gene. Zinc finger proteins are characterized by conserved zinc-binding motifs that facilitate DNA, RNA, or protein interactions, often playing critical roles in transcriptional regulation. While the precise biological functions of ZNF595 remain under investigation, its structural features suggest involvement in DNA binding and gene expression modulation. The protein contains multiple C2H2-type zinc finger domains, typically clustered at the N- or C-terminus, which mediate sequence-specific nucleic acid recognition.
Studies indicate ZNF595 may participate in developmental processes or cellular differentiation, though its specific targets and pathways are not fully elucidated. Some research links zinc finger proteins like ZNF595 to neurodevelopment, cancer progression, or epigenetic regulation, but direct evidence for ZNF595's role in these contexts is limited. Recombinant ZNF595 protein, produced via heterologous expression systems (e.g., *E. coli* or mammalian cells), enables functional studies such as DNA-binding assays, protein interaction screens, or cellular localization experiments.
Despite its unclear physiological significance, recombinant ZNF595 serves as a tool for exploring zinc finger protein mechanics and gene regulation networks. Current efforts focus on characterizing its binding motifs, post-translational modifications, and potential associations with genetic disorders. Further research is needed to define its contributions to normal and pathological states.
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