关键信息
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基因名
ChGn
- 应用
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别名
4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT 1; beta4GalNAcT; Beta4GalNAcT-1; Beta4GalNAcT1; CGAT1_HUMAN; ChGn; Chondroitin beta-1; Chondroitin beta1 4 N acetylgalactosaminyltransferase; Chondroitin beta1 4 N acetylgalactosaminyltransferase 1; Chondroitin sulfate N acetylgalactosaminyltransferase 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TDX6
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表达区间
1-297aa
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氨基酸序列
MMMVRRGLLAWISRVVVLLVLLCCAISVLYMLACTPKGDEEQLALPRANSPTGKEGYQAVLQEWEEQHRNYVSSLKRQIAQLKEELQERSEQLRNGQYQASDAAGLGLDRSPPEKTQADLLAFLHSQVDKAEVNAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALETLNNPAENSPNHRPYTASDFIEGIYRTERDKGTLYELTFKGDHKHEFKRLILFRPFGPIMKVENEKLNMANTLINVIVPLAKRVDKFRQFMQNFRPADEVFRCVPLSP
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分子量
58.41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ChGn, or Chitinase-like protein, has gained significant attention in recent years due to its potential roles in various biological processes, including inflammation, tissue remodeling, and immune response. Initially identified as a member of the family of chitinases, ChGn is characterized by its unique structure that lacks chitinase activity but retains the ability to bind chitin and other carbohydrate ligands. Research has shown that ChGn is expressed in multiple tissues, and its levels can vary in response to environmental factors and diseases, particularly in conditions such as asthma, rheumatoid arthritis, and certain cancers. The protein's regulatory functions suggest it could be a novel biomarker for disease progression and a potential therapeutic target. Understanding the molecular mechanisms underlying ChGn's function through recombinant protein studies is crucial for uncovering its role in health and disease. Moreover, recombinant ChGn can serve as a valuable tool in biochemical assays and therapeutic applications, enhancing our ability to decipher its intricate involvement in various physiological and pathological processes. The continued exploration of ChGn's properties and functions could not only advance basic biological knowledge but also pave the way for innovative clinical strategies in disease management.
