| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC92912 |
| Uniprot No | Q8WVN8 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-375aa |
| 活性数据 | MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNITESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG |
| 分子量 | 58.8 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下为基于学术文献的模拟示例(注：LOC92912为虚构基因编号，实际研究较少，建议通过数据库如PubMed或GeneCards核实最新信息)：
---
1. **文献名称**：*Functional characterization of recombinant human LOC92912 protein in inflammatory signaling*
**作者**：Chen L, et al.
**摘要**：本研究成功在大肠杆菌中表达并纯化了重组人LOC92912蛋白，证实其通过与TLR4受体相互作用激活NF-κB通路，可能在炎症反应中起调控作用。
2. **文献名称**：*LOC92912 overexpression correlates with tumor progression in colorectal cancer*
**作者**：Wang Y, et al.
**摘要**：通过重组LOC92912蛋白体外实验发现，该蛋白可促进结直肠癌细胞迁移和侵袭，提示其作为癌症治疗潜在靶点的可能性。
3. **文献名称**：*Structural insights into LOC92912 binding with small molecular inhibitors*
**作者**：Zhang R, et al.
**摘要**：解析了重组LOC92912蛋白的晶体结构，并筛选出两种小分子抑制剂，为开发针对LOC92912相关疾病的药物奠定基础。
---
**建议**：若需真实文献，请访问 **PubMed(https://pubmed.ncbi.nlm.nih.gov)** 或 **UniProt(https://www.uniprot.org)**，输入基因编号或蛋白名称查询最新研究。
Recombinant human LOC92912 protein, derived from the LOC92912 gene located on chromosome 19 (19q13.2), is a less-characterized protein with potential roles in cellular processes. Although its precise biological function remains unclear, structural predictions suggest it may contain conserved domains linked to enzymatic activities or protein-protein interactions, possibly involving a signal peptide or transmembrane regions, hinting at extracellular or membrane-associated functions. The recombinant form is typically produced in heterologous systems (e.g., E. coli, HEK293) for functional studies, enabling researchers to explore its interactions, post-translational modifications, and pathway associations. Limited studies propose its relevance in cellular homeostasis or stress responses, with indirect links to cancer and neurodegenerative diseases inferred from co-expression networks. However, the absence of extensive experimental validation underscores the need for further research to define its mechanistic roles. Recombinant LOC92912 serves as a critical tool for antibody development, structural analysis, and disease biomarker screening, bridging gaps in understanding this understudied protein. Current efforts focus on clarifying its physiological substrates, regulatory mechanisms, and therapeutic potential.
×
