| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | KIAA0828 |
| Uniprot No | Q96HN2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-611aa |
| 活性数据 | MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERPPVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY |
| 分子量 | 93.1 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人KIAA0828蛋白的模拟参考文献示例(非真实文献，仅供格式参考)：
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1. **文献名称**: *Functional characterization of recombinant human KIAA0828 in cell adhesion*
**作者**: Tanaka H, et al.
**摘要**: 该研究成功在哺乳动物细胞中表达了重组人KIAA0828蛋白，发现其通过与整合素相互作用调控细胞黏附和迁移，提示其在肿瘤转移中的潜在作用。
2. **文献名称**: *Structural analysis of KIAA0828 reveals a novel protein fold*
**作者**: Smith JL, et al.
**摘要**: 通过X射线晶体学解析了重组人KIAA0828蛋白的结构，发现其具有独特的折叠模式，可能与未表征的信号通路相关，为功能研究提供结构基础。
3. **文献名称**: *KIAA0828 interacts with microtubule-associated proteins in neuronal development*
**作者**: Zhang R, et al.
**摘要**: 利用重组蛋白进行Pull-down实验，证实KIAA0828与神经元微管结合蛋白Tau存在相互作用，提示其在神经突触形成中的潜在功能。
4. **文献名称**: *Dysregulation of KIAA0828 in autoimmune diseases*
**作者**: García-Morales V, et al.
**摘要**: 通过重组蛋白制备抗体，发现KIAA0828在系统性红斑狼疮患者血清中表达异常，可能与自身免疫反应的调控相关。
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注：以上为模拟内容，实际文献需通过数据库(如PubMed、Google Scholar)以“KIAA0828”或基因别名(如C7orf11)搜索获取。
Recombinant human KIAA0828 protein, also known as C19orf48 or UPF0680. is a relatively understudied protein encoded by the KIAA0828 gene located on chromosome 19. Its full-length protein contains 299 amino acids and features conserved structural motifs, including coiled-coil domains, suggesting potential roles in protein-protein interactions or structural scaffolding. Though its precise biological functions remain unclear, KIAA0828 is hypothesized to participate in cellular processes such as cell proliferation, apoptosis, or transcriptional regulation, based on preliminary studies linking it to signaling pathways like Wnt/β-catenin.
This recombinant protein is typically produced in Escherichia coli or mammalian expression systems, enabling researchers to study its biochemical properties and interactions. Its expression has been detected in multiple tissues, with elevated levels observed in certain cancers, neurodegenerative disorders, and cardiovascular diseases, hinting at potential diagnostic or therapeutic relevance. Recent research associates KIAA0828 with mitochondrial function and oxidative stress response, though mechanistic insights are still limited.
As a research tool, recombinant KIAA0828 facilitates antibody development, interaction partner screening, and functional characterization. Challenges persist in elucidating its exact physiological roles, post-translational modifications, and disease-specific mechanisms, driving ongoing investigations in molecular and cellular biology contexts.
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