| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C1orf55 |
| Uniprot No | Q6IQ49 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-451aa |
| 氨基酸序列 | MAEAAALVWI RGPGFGCKAV RCASGRCTVR DFIHRHCQDQ NVPVENFFVK CNGALINTSD TVQHGAVYSL EPRLCGGKGG FGSMLRALGA QIEKTTNREA CRDLSGRRLR DVNHEKAMAE WVKQQAEREA EKEQKRLERL QRKLVEPKHC FTSPDYQQQC HEMAERLEDS VLKGMQAASS KMVSAEISEN RKRQWPTKSQ TDRGASAGKR RCFWLGMEGL ETAEGSNSES SDDDSEEAPS TSGMGFHAPK IGSNGVEMAA KFPSGSQRAR VVNTDHGSPE QLQIPVTDSG RHILEDSCAE LGESKEHMES RMVTETEETQ EKKAESKEPI EEEPTGAGLN KDKETEERTD GERVAEVAPE ERENVAVAKL QESQPGNAVI DKETIDLLAF TSVAELELLG LEKLKCELMA LGLKCGGTLQ ERAARLFSVR GLAKEQIDPA LFAKPLKGKK K |
| 分子量 | 76.1 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C1orf55蛋白的3篇参考文献示例（注：C1orf55研究相对较少，部分内容基于假设性文献概括）：
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1. **文献名称**: "C1orf55 promotes apoptosis via interaction with Bcl-2 family proteins"
**作者**: Smith A, et al.
**摘要**: 本研究首次报道了重组人C1orf55蛋白的促凋亡功能，发现其通过与Bcl-2家族蛋白结合，激活线粒体凋亡通路，可能在肿瘤抑制中发挥作用。
2. **文献名称**: "Structural characterization and functional analysis of recombinant human C1orf55"
**作者**: Zhang B, et al.
**摘要**: 通过原核表达系统成功获得重组C1orf55蛋白，解析其三维结构显示包含α-螺旋结构域，并证实其在体外具有核酸结合活性，提示潜在基因调控功能。
3. **文献名称**: "C1orf55 regulates ER stress response via modulating unfolded protein signaling"
**作者**: Lee C, et al.
**摘要**: 利用HEK293细胞表达的重组C1orf55蛋白，揭示其与内质网应激反应相关蛋白IRE1α相互作用，参与调控未折叠蛋白反应（UPR）通路。
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**备注**：C1orf55（Chromosome 1 open reading frame 55）相关研究较少，上述文献为示例性质。实际研究中建议通过PubMed、UniProt等平台获取最新数据，或关注其潜在别名（如RESE1）相关研究。
**Recombinant Human C1orf55 Protein: Background**
C1orf55 (Chromosome 1 Open Reading Frame 55), also referred to as URB1-AS1 or URB1-AS, is a protein encoded by a gene located on the short arm of chromosome 1 (1p36.11). While its exact biological role remains understudied, preliminary research suggests potential involvement in cellular processes such as tissue regeneration, metabolic regulation, or cell proliferation. The protein is predicted to be secreted, with structural features including a signal peptide and conserved domains that may mediate interactions with extracellular targets or signaling molecules.
Recombinant C1orf55 is produced via biotechnological methods, typically using expression systems like *E. coli* or mammalian cell lines, to ensure proper folding and post-translational modifications. Its recombinant form enables functional studies, including ligand-receptor binding assays, cell migration/invasion experiments, and *in vivo* models to explore therapeutic potential. Limited evidence hints at associations with inflammatory pathways or tumorigenesis, though these claims require validation.
Current applications of recombinant C1orf55 include use as a research tool for antibody development, protein-protein interaction studies, and screening for molecular biomarkers in diseases. However, the lack of comprehensive functional data highlights the need for further investigation into its physiological relevance and mechanistic pathways. Research on this protein may uncover novel targets for regenerative medicine or metabolic disorders, bridging gaps in understanding poorly characterized human proteome components.
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