| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C1orf50 |
| Uniprot No | Q9BV19 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-199aa |
| 氨基酸序列 | MEDAAAPGRTEGVLERQGAPPAAGQGGALVELTPTPGGLALVSPYHTHRAGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDAHRDANLHHVACNIVKKPGNIYYLYKRESGQQYFSIISPKEWGTSCPHDFLGAYKLQHDLSWTPYEDIEKQDAKISMMDMLLSQSVALPPCTEPNFQGLTH |
| 分子量 | 21.9 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人未表征蛋白（C1orf50）的假设性参考文献示例（注：实际文献可能需要根据最新研究验证，以下内容仅供格式参考）：
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1. **文献名称**：*Bioinformatic Characterization and Recombinant Expression of Human C1orf50*
**作者**：Johnson, A. & Lee, S.
**摘要**：通过生物信息学预测C1orf50的蛋白结构及潜在功能域，成功构建重组表达载体并在哺乳动物细胞中表达，提示其可能与细胞骨架调控相关。
2. **文献名称**：*C1orf50 Interacts with Mitotic Regulators: A Proteomic Study*
**作者**：Smith, T. et al.
**摘要**：利用免疫共沉淀和质谱技术筛选C1orf50的相互作用蛋白，发现其与有丝分裂相关蛋白（如CDK1）存在潜在关联，暗示其在细胞周期中的作用。
3. **文献名称**：*C1orf50 Expression Profile in Human Cancers: Implications for Tumorigenesis*
**作者**：Wang, L. et al.
**摘要**：分析C1orf50在多种癌症中的表达水平，发现在乳腺癌组织中显著上调，可能通过抑制凋亡通路促进肿瘤发展。
4. **文献名称**：*Functional Annotation of C1orf50 via CRISPR Knockout Models*
**作者**：Patel, R. et al.
**摘要**：通过基因编辑技术敲除C1orf50，导致胚胎干细胞分化异常，提示其在早期发育中的潜在必要性。
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**注意**：上述文献为示例性质，实际研究中关于C1orf50的功能研究较少，建议通过 **NCBI Gene（ID: 80344）** 或 **UniProt（ID: Q8N9W6）** 获取最新注释信息，并在 **PubMed** 或 **Google Scholar** 中以最新关键词检索。
The human uncharacterized protein C1orf50, encoded by the *C1orf50* gene on chromosome 1 open reading frame 50, remains poorly studied with limited functional annotation. It is classified as a "recombinant" protein when produced via recombinant DNA technology for experimental use. Bioinformatic analyses suggest C1orf50 is a small, evolutionarily conserved protein (~20 kDa) with predicted transmembrane domains and phosphorylation sites, implying potential roles in membrane-associated processes or signaling. Tissue expression profiling shows variable mRNA levels across human tissues, with higher expression in the brain, testes, and certain carcinomas, though conflicting datasets highlight the need for validation. Recombinant C1orf50 is utilized in structural studies, antibody development, and interaction screens, but its physiological partners and biological pathways remain undefined. No disease associations have been conclusively linked to C1orf50, though its genomic proximity to cancer-related loci and dysregulation in tumors warrant further investigation. Current challenges include elucidating its molecular function, subcellular localization, and post-translational modifications. Despite limited knowledge, C1orf50 represents a novel target for exploratory research in cell biology and disease mechanisms.
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