关键信息
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基因名
EphA6
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简介
EphA6 Protein, a receptor tyrosine kinase, engages in promiscuous binding with GPI-anchored ephrin-A ligands, facilitating contact-dependent bidirectional signaling. EphA6 mediates intricate signaling exchanges between cells, playing a crucial role in diverse cellular processes through both forward and reverse signaling pathways. EphA6 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EphA6 protein, expressed by HEK293 , with C-hFc labeled tag.
- 应用
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别名
Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; Epha6
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种属
Mouse
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
AAB53836.1
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表达区间
S28-Q546
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蛋白长度
Partial
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分子量
110 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
EphA6 is a member of the Eph receptor tyrosine kinase family, which plays crucial roles in various biological processes, including cell adhesion, migration, and involvement in neural development. The EphA6 receptor has gained attention due to its unique expression patterns in the brain and its potential implications in neurodevelopmental disorders and tumors. Research on EphA6 recombinant protein has intensified to elucidate its structural and functional properties, which could provide insights into its signaling mechanisms and biological roles. By studying EphA6 in vitro, researchers aim to understand its interactions with Ephrin ligands and other cellular pathways that may influence neuronal connectivity and plasticity. Furthermore, the recombinant form of this protein facilitates the development of therapeutic approaches targeting EphA6 pathways, offering potential avenues for treating conditions linked to its dysregulation. Overall, the investigation of EphA6 recombinant protein is essential for advancing our understanding of its roles in health and disease, paving the way for novel interventions in neurobiology and oncology.
