Rabbit Polyclonal (DANRE)Eva1a Antibody

The DANRE (Danio rerio) Eva1a antibody is a specialized tool used in zebrafish research to study the expression and function of the Eva1a protein, a homolog of the mammalian epithelial V-like antigen 1 (EVA1A). Eva1a is a transmembrane protein implicated in cell adhesion, apoptosis regulation, and tissue development. In zebrafish, it plays critical roles during embryogenesis, particularly in neural development, organogenesis, and cell-cell communication. The antibody is typically generated by immunizing host animals (e.g., rabbits or mice) with a synthesized peptide or recombinant protein corresponding to a conserved region of the zebrafish Eva1a protein. It is validated for applications such as immunohistochemistry, Western blotting, and immunofluorescence to visualize spatial-temporal protein expression patterns in developing embryos or adult tissues. Researchers utilize this antibody to investigate Eva1a's involvement in developmental pathways, disease models (e.g., neurodegeneration, cancer), and its interaction with signaling molecules like Wnt or Notch. Its specificity is confirmed through knockout controls or siRNA-mediated knockdown experiments. The DANRE Eva1a antibody has become essential for advancing studies in evolutionary biology, developmental genetics, and regenerative medicine using zebrafish as a model organism.