关键信息
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基因名
AHNAK
- 应用
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别名
AHNAK；PM227；Neuroblast differentiation-associated Protein AHNAK
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q09666-2
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表达区间
1-149aa
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氨基酸序列
MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVK EGDQIVGATIYFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTW TREVFSSCSSEVVLNTPQPSALECKDQNKQKEASSQAGAVSVSTPNAGL
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
AHNAK, a large scaffolding protein, has garnered significant attention in recent years due to its diverse roles in cellular processes. Initially identified as a neuronal protein, AHNAK is now recognized for its involvement in various functions, including cell adhesion, migration, and proliferation. Aberrant expression of AHNAK has been associated with several cancers, suggesting its potential as a biomarker and therapeutic target. Research has indicated that AHNAK interacts with numerous signaling pathways and cellular components, influencing processes such as tumor progression and metastasis. The complexity of its structure, comprising multiple repeats and functional domains, has spurred interest in generating recombinant forms of AHNAK for detailed functional studies. Such studies aim to elucidate its precise molecular mechanisms and interactions within cells, providing insights into its role in normal physiology and disease. Understanding AHNAK’s function at the molecular level could lead to novel strategies for cancer diagnosis and treatment, underscoring the significance of ongoing research into this multifaceted protein.
