WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, Complex I-20kD, CI-20kD, NADH-ubiquinone oxidoreductase 20 kDa subunit, PSST subunit, NDUFS7 |
Entrez GeneID | 374291 |
WB Predicted band size | 23.6kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This NDUFS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-146 amino acids from the Central region of human NDUFS7. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于NDUFS7抗体的3篇代表性文献摘要概览:
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**1. 文献名称**:*Mitochondrial complex I deficiency caused by a deleterious NDUFS7 variant*
**作者**:Thompson K, et al.
**摘要**:该研究利用NDUFS7抗体通过Western blotting和免疫组化技术,发现某遗传性线粒体疾病患者存在复合物I亚基NDUFS7表达显著降低,证实其与复合物I功能缺陷及临床表型相关。
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**2. 文献名称**:*NDUFS7 mutations alter mitochondrial membrane protein stability in Leigh syndrome*
**作者**:Ghezzi D, et al.
**摘要**:研究通过NDUFS7抗体检测患者成纤维细胞中线粒体复合物I的组装状态,发现特定突变导致NDUFS7蛋白稳定性下降,揭示了Leigh综合征中能量代谢障碍的分子机制。
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**3. 文献名称**:*Antibody-based profiling of mitochondrial respiratory chain complexes in Parkinson's disease*
**作者**:Zheng B, et al.
**摘要**:该文献使用NDUFS7抗体对帕金森病患者脑组织进行蛋白质分析,发现复合物I亚基表达水平与神经元退行性病变程度呈负相关,提示其作为疾病生物标志物的潜力。
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**备注**:以上文献为示例性质,实际引用时需核实具体来源及细节。如需精准文献,建议在PubMed等数据库以“NDUFS7 antibody”及“complex I deficiency”为关键词检索近年研究。
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