| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | CCAAT/enhancer-binding protein delta, C/EBP delta, Transcription factor CELF, Cebpd, Celf |
| Entrez GeneID | 25695 |
| WB Predicted band size | 28.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Rat Cebpd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of rat Cebpd. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇涉及CEBPD抗体的研究文献摘要，供参考：
1. **文献名称**：C/EBPδ promotes oncogenic signaling through its pro-inflammatory activity in colorectal cancer
**作者**：Papaioannou G et al.
**摘要**：研究揭示CEBPD在结直肠癌中通过调控炎症因子IL-6和IL-8促进肿瘤进展，Western blot和免疫组化实验使用CEBPD抗体验证其蛋白表达与患者预后不良相关。
2. **文献名称**：The role of C/EBPδ in the cellular stress response
**作者**：Ramji DP et al.
**摘要**：探讨CEBPD在氧化应激和DNA损伤中的调控机制，通过免疫荧光和ChIP实验证实CEBPD抗体检测到其在应激条件下核内聚集并激活下游基因。
3. **文献名称**：C/EBPδ regulates adipogenesis through interaction with PPARγ
**作者**：Rosen ED et al.
**摘要**：研究脂肪分化中CEBPD与PPARγ的协同作用，免疫共沉淀实验使用特异性CEBPD抗体证明两者直接结合，调控脂类代谢相关基因表达。
提示：如需具体文献来源(期刊、年份)，建议在PubMed中搜索「CEBPD antibody」或结合研究领域关键词(如cancer/inflammation)，筛选抗体应用部分明确提及Commercial CEBPD antibody(如Santa Cruz的sc-636或Cell Signaling的抗体编号)的论文。部分厂商官网(如CST)也会列出抗体在已发表研究中的应用案例。
The C/EBPδ antibody (often denoted as CEBPD or CEBP delta) is a crucial tool in studying the CCAAT/enhancer-binding protein delta, a transcription factor involved in diverse cellular processes. C/EBPδ belongs to the C/EBP family of basic leucine zipper (bZIP) proteins and plays a key role in regulating inflammation, differentiation, apoptosis, and metabolic homeostasis. It is activated in response to stress signals, cytokines (e.g., IL-6. TNF-α), and hormonal cues, influencing genes associated with immune responses, cell cycle arrest, and tissue remodeling.
The R Cebpd antibody, typically raised in rabbits or mice, is designed to detect endogenous C/EBPδ proteins in applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Its specificity is validated using knockout controls or peptide-blocking assays to ensure accurate targeting. Research utilizing this antibody has elucidated C/EBPδ's dual roles in cancer (pro-tumorigenic or tumor-suppressive depending on context), metabolic disorders (e.g., insulin resistance), and acute-phase responses. It also contributes to understanding circadian rhythm regulation and macrophage polarization. Recent studies highlight its interaction with signaling pathways like STAT3 and NF-κB, making it a focal point in therapeutic targeting for inflammatory diseases and malignancies. Proper validation and species reactivity (human, mouse, rat) are critical for experimental reproducibility.
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