Mouse Monoclonal FAPB3(Ascites) Antibody

The FAPB3 (Ascites) antibody is a tool used to detect Fatty Acid Binding Protein 3 (FABP3), also known as mammary-derived growth inhibitor-related protein (MDGI). FABP3 belongs to a family of intracellular lipid-binding proteins involved in fatty acid transport, metabolism, and signaling. While primarily studied in cardiac and muscle tissues, FABP3 has gained attention in cancer research due to its aberrant expression in certain malignancies. In ascites—fluid accumulation in the peritoneal cavity associated with advanced cancers like ovarian or gastric—FABP3 may play a role in tumor microenvironment interactions, lipid-mediated signaling, or metastasis. The FAPB3 antibody is utilized in techniques like Western blotting, immunohistochemistry (IHC), or immunofluorescence (IF) to assess FABP3 levels in ascitic fluid or tumor tissues. Its detection aids in understanding cancer cell adaptation to lipid-rich ascites environments, potentially revealing mechanisms of drug resistance or metastatic spread. However, FABP3's specific role in ascites-related pathologies remains under investigation, with studies suggesting both tumor-suppressive and pro-survival functions depending on context. This antibody serves as a critical reagent for exploring FABP3's diagnostic or therapeutic potential in cancers complicated by ascites.