Rabbit Polyclonal FCSD2 Antibody

The FCSD2 antibody targets the FCSD2 (Fascin C-terminal domain-containing protein 2), a less-characterized protein implicated in cytoskeletal regulation and cellular dynamics. While its exact biological role remains under investigation, FCSD2 is hypothesized to interact with actin-binding proteins like fascin, potentially influencing cell motility, adhesion, and structural organization. The antibody is typically developed in rabbit or mouse hosts using immunogenic peptides or recombinant protein fragments corresponding to conserved regions of FCSD2. Validated for applications such as Western blotting, immunofluorescence, and immunohistochemistry, it aids in detecting endogenous FCSD2 expression across tissues, with observed prominence in epithelial and neuronal cells. Recent studies suggest FCSD2 may contribute to pathological processes, including cancer metastasis and neurodevelopmental disorders, though mechanistic insights are limited. Commercial availability and research-grade formulations facilitate its use in exploratory studies, often paired with knockdown/overexpression models to correlate protein localization with functional phenotypes. Ongoing efforts focus on elucidating FCSD2’s binding partners and post-translational modifications to clarify its role in cellular homeostasis and disease pathways.