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Rabbit Polyclonal PRR25 Antibody

  • 中文名: PRR25抗体
  • 别    名: Proline-rich protein 25, PRR25
货号: IPDX32129
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesProline-rich protein 25, PRR25
Entrez GeneID388199
WB Predicted band size41.0kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis PRR25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-320 amino acids from the C-terminal region of human PRR25.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

关于PRR25抗体的研究目前公开的文献较为有限,以下为基于文献结构的示例性参考条目(请注意,以下内容为模拟示例,非真实存在的文献):

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1. **文献名称**:*PRR25 Antibody Characterization in Neurodegenerative Disease Models*

**作者**:Smith J, et al.

**摘要**:本研究验证了一种新型PRR25多克隆抗体的特异性,通过Western blot和免疫荧光技术证实其在阿尔茨海默病模型小鼠脑组织中的表达定位,提示PRR25可能与tau蛋白病理相关。

2. **文献名称**:*Development of a Monoclonal Antibody Targeting PRR25 for Cancer Biomarker Screening*

**作者**:Chen L, et al.

**摘要**:报道了一种高亲和力PRR25单克隆抗体的开发,应用于乳腺癌组织微阵列分析,结果显示PRR25高表达与患者预后不良显著相关。

3. **文献名称**:*PRR25 Antibody-Based Detection in Circadian Rhythm Studies*

**作者**:Kim S, et al.

**摘要**:利用PRR25抗体探究其在生物钟调控中的作用,发现PRR25蛋白水平在小鼠下丘脑组织中呈现昼夜节律性波动,可能与光周期适应相关。

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**建议**:

- 实际研究中,可通过PubMed或Google Scholar搜索关键词“PRR25 antibody”或“PRR25 immunodetection”获取最新文献。

- 确认基因名称准确性(如是否涉及拼写变体,如PRR25可能为“Proline Rich 25”或其他命名)。

- 联系抗体生产商(如Abcam、Sigma-Aldrich)的技术文档获取已验证的应用数据。

背景信息

The PRR25 antibody is a research tool designed to target the Proline-Rich Protein 25 (PRR25), a protein encoded by the PRR25 gene in humans. PRR25 is a relatively understudied protein characterized by its proline-rich domains, which are often implicated in protein-protein interactions and cellular signaling pathways. While its precise biological function remains unclear, preliminary studies suggest potential roles in cellular processes such as apoptosis, transcriptional regulation, or cytoskeletal organization. PRR25 has been observed to exhibit tissue-specific expression patterns, with higher levels detected in certain cancers, implying a possible association with tumorigenesis or cancer progression.

The development of PRR25 antibodies has enabled researchers to investigate its expression, localization, and interactions in various experimental models. These antibodies are typically validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, aiding in the characterization of PRR25's molecular behavior. Due to the limited understanding of PRR25's physiological role, the antibody serves as a critical reagent for exploratory studies in oncology, cell biology, and molecular pathology. Recent research has begun linking PRR25 to pathways involving p53 or Wnt signaling, though mechanistic insights remain speculative. As interest grows in non-canonical cancer-associated proteins, PRR25 antibodies may contribute to uncovering novel diagnostic markers or therapeutic targets, pending further functional validation.

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