WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Proline-rich protein 25, PRR25 |
Entrez GeneID | 388199 |
WB Predicted band size | 41.0kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This PRR25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-320 amino acids from the C-terminal region of human PRR25. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于PRR25抗体的研究目前公开的文献较为有限,以下为基于文献结构的示例性参考条目(请注意,以下内容为模拟示例,非真实存在的文献):
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1. **文献名称**:*PRR25 Antibody Characterization in Neurodegenerative Disease Models*
**作者**:Smith J, et al.
**摘要**:本研究验证了一种新型PRR25多克隆抗体的特异性,通过Western blot和免疫荧光技术证实其在阿尔茨海默病模型小鼠脑组织中的表达定位,提示PRR25可能与tau蛋白病理相关。
2. **文献名称**:*Development of a Monoclonal Antibody Targeting PRR25 for Cancer Biomarker Screening*
**作者**:Chen L, et al.
**摘要**:报道了一种高亲和力PRR25单克隆抗体的开发,应用于乳腺癌组织微阵列分析,结果显示PRR25高表达与患者预后不良显著相关。
3. **文献名称**:*PRR25 Antibody-Based Detection in Circadian Rhythm Studies*
**作者**:Kim S, et al.
**摘要**:利用PRR25抗体探究其在生物钟调控中的作用,发现PRR25蛋白水平在小鼠下丘脑组织中呈现昼夜节律性波动,可能与光周期适应相关。
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**建议**:
- 实际研究中,可通过PubMed或Google Scholar搜索关键词“PRR25 antibody”或“PRR25 immunodetection”获取最新文献。
- 确认基因名称准确性(如是否涉及拼写变体,如PRR25可能为“Proline Rich 25”或其他命名)。
- 联系抗体生产商(如Abcam、Sigma-Aldrich)的技术文档获取已验证的应用数据。
The PRR25 antibody is a research tool designed to target the Proline-Rich Protein 25 (PRR25), a protein encoded by the PRR25 gene in humans. PRR25 is a relatively understudied protein characterized by its proline-rich domains, which are often implicated in protein-protein interactions and cellular signaling pathways. While its precise biological function remains unclear, preliminary studies suggest potential roles in cellular processes such as apoptosis, transcriptional regulation, or cytoskeletal organization. PRR25 has been observed to exhibit tissue-specific expression patterns, with higher levels detected in certain cancers, implying a possible association with tumorigenesis or cancer progression.
The development of PRR25 antibodies has enabled researchers to investigate its expression, localization, and interactions in various experimental models. These antibodies are typically validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, aiding in the characterization of PRR25's molecular behavior. Due to the limited understanding of PRR25's physiological role, the antibody serves as a critical reagent for exploratory studies in oncology, cell biology, and molecular pathology. Recent research has begun linking PRR25 to pathways involving p53 or Wnt signaling, though mechanistic insights remain speculative. As interest grows in non-canonical cancer-associated proteins, PRR25 antibodies may contribute to uncovering novel diagnostic markers or therapeutic targets, pending further functional validation.
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