WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2 |
Entrez GeneID | 1856 |
WB Predicted band size | 78.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是3篇关于DVL2抗体的模拟参考文献(基于公开领域知识框架构建,具体文献需通过学术数据库核实):
1. **《DVL2-mediated Wnt/β-catenin signaling suppression inhibits colorectal cancer metastasis》**
- 作者:Chen, L. et al.
- 摘要:研究利用DVL2特异性抗体阻断Wnt信号通路,发现抑制DVL2可降低β-catenin核转位,从而抑制结直肠癌细胞的迁移和侵袭能力。
2. **《Antibody-based targeting of DVL2 disrupts planar cell polarity in developmental models》**
- 作者:Smith, J.R. & Yamaguchi, T.
- 摘要:通过DVL2抗体的显微注射实验,证明DVL2在胚胎发育中调控细胞极性和组织形态发生,抗体干预导致斑马鱼模型体轴发育异常。
3. **《DVL2 phosphorylation status as a biomarker for Wnt pathway activation in triple-negative breast cancer》**
- 作者:Gupta, S. et al.
- 摘要:开发新型DVL2磷酸化位点特异性抗体,证实其在三阴性乳腺癌中可作为Wnt通路异常激活的生物标志物,与患者预后显著相关。
注:以上为基于DVL2已知功能的模拟参考文献框架,实际文献需通过PubMed/Google Scholar以"DVL2 antibody"+"具体研究领域"为关键词检索获取。建议优先选择近五年内发表的、经同行评审的研究论文。
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