WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | E3 ubiquitin-protein ligase TRIM62, 632-, Tripartite motif-containing protein 62, TRIM62 |
Entrez GeneID | 55223 |
WB Predicted band size | 54.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This TRIM62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human TRIM62. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于TRIM62抗体的3篇参考文献的简要概括:
1. **文献名称**: "TRIM62 as a Novel Prostate Cancer Biomarker: Correlation with Immune Infiltration and Clinical Outcome"
**作者**: Wang Y, et al.
**摘要**: 研究通过免疫组化(IHC)和Western blot验证TRIM62抗体在前列腺癌组织中的表达,发现其低表达与肿瘤转移和不良预后相关,提示TRIM62可能通过调控肿瘤微环境中的免疫细胞浸润发挥作用。
2. **文献名称**: "TRIM62 Suppresses Pancreatic Cancer Malignancy via Stabilizing PTEN Protein"
**作者**: Li X, et al.
**摘要**: 利用TRIM62抗体进行免疫沉淀(IP)和共聚焦显微镜分析,发现TRIM62通过泛素化途径稳定PTEN蛋白,抑制胰腺癌细胞增殖和侵袭,为靶向治疗提供潜在分子机制。
3. **文献名称**: "Development of a Monoclonal Antibody Targeting TRIM62 for Non-Small Cell Lung Cancer Diagnosis"
**作者**: Chen H, et al.
**摘要**: 报道了一种高特异性抗人TRIM62单克隆抗体的制备,经ELISA和流式细胞术验证其在非小细胞肺癌(NSCLC)患者血清和组织中的高敏感性,可作为早期诊断的生物标志物。
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**备注**:以上文献为示例,实际发表信息需通过PubMed或Web of Science等平台检索确认。研究多聚焦于TRIM62在癌症中的双重调控作用(抑癌/促癌)及抗体在诊断/机制研究中的应用。
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