WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | NEDD4-binding protein 3, N4BP3, N4BP3, KIAA0341 |
Entrez GeneID | 23138 |
WB Predicted band size | 60.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This N4BP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human N4BP3. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于N4BP3 (N-term)抗体的虚构参考文献示例(实际文献需通过学术数据库查询):
1. **文献名称**:N4BP3 regulates antiviral immune response via ubiquitin-dependent RNA sensing
**作者**:T. Suzuki et al.
**摘要**:研究揭示N4BP3通过其N端结构域与病毒RNA结合,参与RIG-I信号通路的泛素化调控,利用N4BP3 (N-term)抗体验证其在免疫细胞中的亚定位及功能。
2. **文献名称**:Structural insights into N4BP3-mediated protein degradation in cancer
**作者**:L. Wang et al.
**摘要**:通过N4BP3 (N-term)抗体进行免疫共沉淀实验,证明N4BP3与E3泛素连接酶复合物相互作用,靶向促癌蛋白降解,为肿瘤治疗提供新靶点。
3. **文献名称**:N4BP3 modulates neuronal survival in Alzheimer’s disease models
**作者**:M. Schmidt et al.
**摘要**:利用N4BP3 (N-term)抗体进行Western blot和免疫组化分析,发现N4BP3在阿尔茨海默病模型中通过抑制Tau蛋白异常磷酸化保护神经元。
4. **文献名称**:Development of a novel N-terminal specific antibody for N4BP3 functional studies
**作者**:J. Kim et al.
**摘要**:本文报道了一种高特异性N4BP3 (N-term)抗体的制备与验证,应用于流式细胞术及ChIP-seq,揭示其在DNA损伤修复中的转录调控作用。
(注:以上为模拟内容,实际文献需查询PubMed、Google Scholar等平台,建议结合具体研究背景筛选。)
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