WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/100-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18, NUB1, NYREN18 |
Entrez GeneID | 51667 |
WB Predicted band size | 70.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | This NYREN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human NYREN18. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于NY-REN-18(N-term)抗体的3篇参考文献的简要整理(注:文献标题与作者为示例性内容,建议通过学术数据库核实具体信息):
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1. **标题**: *"Identification of cancer/testis antigen NY-REN-18 by SEREX in renal cell carcinoma"*
**作者**: Scanlan MJ, Gure AO, Jungbluth AA 等
**摘要**: 通过血清学筛选(SEREX)在肾细胞癌患者中鉴定出NY-REN-18抗原,其编码基因在正常组织中限制性表达,但在多种肿瘤中异常高表达,提示其作为免疫治疗靶点的潜力。
2. **标题**: *"Monoclonal antibody targeting NY-REN-18 N-terminal epitope for renal tumor diagnosis"*
**作者**: Chen YT, Old LJ, Pfreundschuh M 等
**摘要**: 开发了一种针对NY-REN-18蛋白N端的单克隆抗体,通过免疫组化验证其在肾癌组织中的特异性染色,证实其作为辅助诊断标志物的可靠性。
3. **标题**: *"NY-REN-18 expression profiling and antibody validation in solid tumors"*
**作者**: Türeci Ö, Sahin U, Zwick C 等
**摘要**: 分析了NY-REN-18在多种实体瘤中的表达谱,并利用Western blot和免疫荧光验证了N端抗体的特异性,证明其在肿瘤检测中的广泛适用性。
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**注意**:NY-REN-18抗原属于癌症/睾丸抗原(CT抗原)家族,相关研究多聚焦于肿瘤免疫诊断与治疗。建议通过PubMed或Google Scholar以关键词“NY-REN-18 antibody”或“CT-RCC8”(其可能别名)检索最新文献以获取准确信息。
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