关键信息
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基因名
FOXA2
- 应用
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别名
FOX-A2; HNF3B; TCF3B; Hepatocyte Nuclear Factor 3,Beta; Transcription factor 3B
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35583
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表达区间
Met1~Ser459
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分子量
53kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FOXA2, also known as Forkhead Box A2, is a transcription factor that plays a critical role in various biological processes, including organogenesis, cell differentiation, and metabolism. Its significance has garnered attention in the context of developmental biology and disease, particularly in relation to diseases such as cancer and metabolic disorders. Recent studies have highlighted FOXA2's involvement in maintaining the identity and function of pancreatic beta cells, making it a potential target for diabetes research. The generation of recombinant FOXA2 protein allows for in-depth exploration of its structural and functional dynamics, enabling researchers to investigate its interactions with other proteins and DNA elements. In particular, understanding how FOXA2 regulates target gene expression provides insights into its role in developmental pathways and cellular responses to environmental stimuli. The recombinant FOXA2 protein serves as a valuable tool for functional assays, structural studies, and therapeutic applications, paving the way for novel interventions in disease management and regenerative medicine. This research area continues to evolve, driven by advancements in molecular biology techniques, and holds promise for uncovering new therapeutic strategies that harness the regulatory capabilities of FOXA2.
